Coated hard capsules are becoming increasingly important for a number of reasons such as administration of new active ingredients, oral vaccination, colon drug delivery or their use in preclinical and clinical trials. The independency of coating composition on capsules filling is the major advantage of this dosage form. In our study, two types of hard capsules (gelatin and hypromellose) were co...

After coating, the resist film contains a remaining solvent concentration depending on the resist, the solvent, the resist film thickness and the resist coating technique. The softbake reduces the remaining solvent content in order to: avoid mask contamination and/or sticking to the mask, prevent popping or foaming of the resist by N2 created during exposure, improve resist adhesion to the subs...

The electrochemical properties of fluoride-coated lithium cobalt oxide [LiCoO2] thin films were characterized. Aluminum fluoride [AlF3] and lanthanum fluoride [LaF3] coating layers were fabricated on a pristine LiCoO2 thin film by using a spin-coating process. The AlF3- and LaF3-coated films exhibited a higher rate capability, cyclic performance, and stability at high temperature than the prist...

PURPOSE The aim of this study was to formulate stable film-coated montelukast sodium (MS) tablets using Opadry(®) yellow 20A82938 (Montikast(®) tablets) and to evaluate their in vitro and in vivo release profile. METHODS MS core tablets were manufactured using a direct compression method. Opadry yellow 20A82938 aqueous coating dispersion was used as the film-coating material. Dissolution of t...

in this paper, zno thin film is deposited on slide glass substrate using the sol-gel process. presenting well-defined orientation of zno thin films nanostructure were obtained by dip coating of zinc acetate dihydrate, monoethanolamine (mea), de-ionized water and isopropanol alcohol. the annealed zno thin films were transparent ca 85-90% in visible range with an absorption edges at about 375 nm....

D. Niblett, S. C. Porter, I. Gabbott, G. Reynolds, T. Morgan, K. Karan, J. Greenamoyer, R. Hach University of Manchester, Ashland Specialty Ingredients, AstraZeneca Purpose Aqueous film coating still remains a complex process in which the process parameters selected can have a major impact on ultimate product quality. In this study, a wide range of processing parameters was performed in order t...

Jet-wiping is a hydrodynamic method for controlling the liquid film thickness in a coating process. In industrial conditions, the jet is generally turbulent. When the jet wipes a liquid film, it usually induces violent film instability called splashing. The instability is characterized by the ejection of droplets from the runback flow. Consequently, it can degrade the final coating quality sinc...

The purpose of this research was to study the aqueous-based film coating of tablets utilizing a laboratoryscale side-vented perforated pan-coating apparatus. The process parameters of potential importance with respect to the final film quality were evaluated by using trial and error method. Tablets were evaluated for coating uniformity (mg), coating process efficiency (%), surface roughness, an...

The aim of the present work was to study the effect of various process parameters on an aqueous-based film coating process of tablets performed in a side-vented perforated pan-coating apparatus. Results of preliminary trials indicate that spray rate, inlet air temperature, percentage solid content, atomizing air pressure and speed of rotation affected characteristics of coating. A 3 full factor...

Coating shrinkage upon drying is a phenomenon well known to the paper coating industry where it often causes changes in the final structure of the coating layer, leading to poor results in terms of gloss, light scattering, surface strength, coverage and printability. The aim of this paper is to improve the understanding of coating shrinkage by measuring the forces related to the capillarity, ac...