The initial, nanometer-sized connection between the plasma membrane and a hormone- or neurotransmitter-filled vesicle -the fusion pore- can flicker open and closed repeatedly before dilating or resealing irreversibly. Pore dynamics determine release and vesicle recycling kinetics, but pore properties are poorly known because biochemically defined single-pore assays are lacking. We isolated sing...

Dilated pore was originally designated as a secondary or acquired trichoepithelioma by Winer, represents an appendageal tumor with differentiation towards hair structures. It is clinically characterized by having the appearance of a large blackhead filled with keratinous material. To the best of our knowledge, there has been no report of a dilated pore with four openings. We herein describe suc...

Sound propagation i gas-filled capillary-tube-type orous media was investigated. The capillary tubes were taken to be nominally straight with very small pores in the walls of the capillary tubes. The complex wave number and the characteristic mpedance of such media were evaluated. Application to ceramic samples having capillary pores with square cross sections and porous walls is developed as a...

Flow and transport processes in porous media depend on the geometric properties of their pores, where the diameters typically range from micrometers to millimeters. In this study, we mapped the pore structure of glass bead and sand columns using tomography with X-rays, thermal neutrons, and synchrotron radiation. Utilizing X-rays from tubes, we mapped two 2.5and 5.3-cm-diam. sand samples that c...

Ultrathin sections of Lowicryl K4M embedded cultured 3T3 cells, human keratinocytes and mouse/rat liver tissue were incubated with polyspecific primary antibodies against p62 and other nucleoporins followed by 10 nm gold labeled secondary antibodies. By quantitatively evaluating both cross sections and tangential sections of the NPC, we found that irrespective of the cell type antibodies predom...