Tumor cells that invade the bloodstream and reach distant organs are the seeds of death. " Patients with cancer … don't die from the primary tumor, they always die from metastases, " said Leon Terstappen, M.D., Ph.D., chief scientific officer of Immunicon, a Pennsylvania biotechnology company. Because tumor cells make their way to the site of distant metastases via the bloodstream, " there must...

BACKGROUND Approximately 20% of leg ulcers remain unresponsive to the best conservative standard of care. So far, these patients could either receive conventional skin grafts or had to accept their intractable wound. Skin substitutes from cell culture may represent a promising alternative to heal a major part of these patients on a non-surgical, potentially more cost-effective basis. OBJECTIV...

Field trial design is a crucial consideration in efficient, cost-effective plant breeding programs. Design properties and specific designs relevant to plant breeding are considered. Good field designs are important at all major stages of a plant breeding program from the earlier stages of screening hundreds, possibly thousands of entries through identification of a few elite selections for rele...

Efficacy of premiliking teat disinfection (predipping) with good udder preparation was compared with good udder preparation alone on four well-managed, commercial dairy farms. Three teat dip formulations containing iodophor were used for predipping. Predipping reduced the rate of intramammary infection with major mastitis pathogens approximately 54%. Infection rate with esculin-positive strepto...