This report describes methods which have been developed in this laboratory for the determination of antifibrinolysin activity in plasma. Using these methods, studies have been made of the antifibrinolysin activity in the plasma of the alligator (Alligator inississippiensis), guinea pig (genus Cavia), cow (Bos taurus), rat (Rattus norvegicus, Sprague-Dawley strain), frog (Rana pipiens), man (whi...

THE magnlitude of the literature dealing with deep thrombophlebitis of the lower extremities and its complications reflects not onily the interest that this disorder commands among physicians but also the extensive controversy that it has generated. Controversy surrounds even such fundamental problems as the pathogenesis of venous thromboembolism, the natural course of the process, and the adeq...

That haemolytic streptococci of human origin produce a substance capable of liquefying human fibrin was first demonstrated by Tillet and Garner in 1933. The fibrin from patients recently recovered from haemolytic streptococcal infection was in many cases found to be resistant to the action of this fibrinolysin. and confirmed these preliminary observations, and demonstrated antifibrinoly-sin in ...

The extracellular production of hyaluronidase and chondroitin sulfatase was demonstrated in all of the subspecies of Bacteroides fragilis tested with the exception of B. fragilis subsp. vulgatus. Elastase was found only in one strain of B. coagulans tested. This appears to be the first report of these enzyme activities in this genus. Additional enzymes found to be produced by certain members ot...