background: seroma formation is a common complication after breast cancer surgery. several techniques such as tube drainage, fibrin sealant and suturing methods have been employed to prevent or reduce seroma formation. capitonnage, a suturing method widely used following hydatid cyst removal, has been used after breast surgery in limited studies. our aim was to compare the effectiveness of tube...

Introduction: Vesicovaginal fistula remains a challenge in surgical therapy. In this study autologous platelet rich plasma and platelet rich fibrin glue were used as a minimally invasive approach for vesicovaginal fistula closure. Materials and Methods: Data including age, parity, ICIQ-UI (International Consultation on Incontinence Questionnaire-urinary incontinence), ICIQ-QOL (Internation...

Introduction: One of the most common complications following total laryngectomy is pharyngocutaneous fistula (PCF). Various methods have been proposed to treat this disorder in recent studies, including a range of simple and conservative treatments to more aggressive therapies, such as various surgical procedures. One of the most innovative and least developed methods is the use of plasma...

purpose : to evaluate the efficiency and safety of using autologous fibrin glue for attachment of a conjunctival autograft in primary pterygium surgery methods : in this prospective interventional case series, 15 eyes from 13 patients with primary nasal pterygium were included for conjunctival autograft surgery. on the operation day, thrombin and fibrinogen were prepared from the patient’s own ...

purpose : to determine the efficacy of fibrin glue in corneal perforations up to 3 mm in diameter methods : a case series study was performed on corneal perforations up to 3 mm who were admitted at farabi hospital- tehran. age, visual acuity, presence and size of corneal thinning, corneal epithelial defect, size and depth of corneal infiltration, site and size of corneal perforation, corneal va...

Background: Recent improvement in treatments of cancer has significantly increased survival rates of cancer patients. Unfortunately these treatments such as chemotherapy and radiotherapy can sever damage to the ovaries. Ovarian cryopreservation prior to chemo/ radiotherapy and auto-transplantation post-treatment can restore fertility to cancer patients. Hypoxia in the transplant from delayed re...

introduction: natural biomaterials and growth factors are key factors in tissue engineering. the objective of the present study was to evaluate transforming growth factor beta 1 (tgf-β1) and curcumin on proliferation and differentiation of nasal-derived chondrocyte seeded on the fibrin glue scaffold. methods: chondrocytes were isolated from nasal samples. nasal-derived chondrocytes were seeded ...

objective- this study aimed to evaluate the feasibility of using platelet rich fibrin membrane as a novel on-lay patching biomaterial in canine esophagotomy and its effects on esophageal wound healing. design- experimental study. animals- eight adult mixed breed dogs of both sexes equally allocated to control and treatment groups. procedures- longitudinal incisions measuring 3 cm were made in t...

platelets are a natural source of growth factors and cytokines that promote wound healing, and platelet-rich fibrin contains concentrated growth factors. growth factors in platelet-rich fibrin may promote wound repair. in this study the effect of platelet-rich fibrin was evaluated in a dog model of cutaneous incisional wounds using histology and semi-quantitative evaluation. a pair of ten-centi...

KFGS (Keratinocyte fibrin glue suspension) and FKFGS (Fibroblast keratinocyte fibrin glue suspension) methods were performed in this study. Materials and Methods: Four healthy adult horses were used in this study (350 ± 117). Fibroblast cells have been separated by explant culture method from neck, keratinocyte cells have been separated by enzyme digestion from lib skin samples and Fibrinogen h...