â  multiple hepatic lesions and fever of unknown origin

Kikuchi Fujimoto Disease (KFD), also known as necrotic histiocystic lymphadenitis, is a condition with unknown etiology. Probably, infectious, viral, and also autoimmune etiologies, especially lupus erythematosus, contribute to this disorder. The common signs are lymphadenopathy along with fever and leukopenia. Our case was a13-year-old boy with fever of unknown origin. He underwent ordinary fe...

The original criteria for fever of unknown origin (FUO) as set forth in 1961 by Petersdorf and Beeson were fever higher than 38.3°C on several occasions of at least 3 weeks’ duration and uncertain diagnosis after 1 week of study in the hospital (1). This definition was later revised, and the criterion of 1 week of hospitalization has been replaced by 3 days of hospitalization or three outpatien...

There are many potential causes of FUO. Most cases are due to unusual presentations of common diseases rather than rare or exotic diseases. The key to establishing the diagnosis is a careful history and careful repeated examinations followed by targeted investigations.

概要 近年,診 断技 術の進歩 お よび疾患概 念の変化 に よ り,不 明熱 の原 因疾患 は変貌 して い る と推測 され る.そ こで不 明熱 の原因疾 患の 変遷 を明 らかに し,診 断上 の問題 点 を検 討 した. 1971-1982 の11年 間 に北 里大学 田崎内科 に入院 した患 者6695例 よ りPetersdorfら の定 義 を満 足す る症例79例 を抽 出 して解析 した.不 明熱 の原因疾患ば 感染 症35%(28例),結 合組織 病22% (17例),悪 性腫瘍14%(11例),そ の他8%(6例)お よび診断不能22%(17例)で あ つた.感 染症 が最 も多 かつた が,年 次別 にみ ると感染 症の比率 は低 下す る傾 向 にあ り,か わつ て結合組 織病 と悪性腫瘍 が増加す る傾向 にあつた.各 群 を構成す る主な疾 患は,感...

Strongyloides is endemic in parts of the United States. Most often it is asymptomatic but it has a wide range of clinical presentations. Because of the unusual capacity of strongyloides for autoinfection, it can cause hyperinfection, when it effects the pulmonary and gastrointestinal systems, or disseminated infection, when other organs are involved. Both hyperinfection and disseminated strongy...

This study involved 115 cases of fever of unknown origin (FUO) patients who were admitted to the Department of Medicine, Siriraj Hospital from May 1999 to November 2000. Among the patient sera screened by ELISA for IgG Hantavirus, five were positive for IgG Hantavirus-reacting antibodies and eight tested positive for IgM Hantavirus-reacting antibodies. One serum had both IgG and IgM antibodies....

Dengue has been reported from plains as well as hilly regions of India including some parts of Northeast India. In July-August 2012, outbreak of fever with unknown origin (FUO) indicative of Dengue was reported in Pasighat, East Siang district of Arunachal Pradesh (AP) state. Serum samples (n = 164) collected from patients from Health Training and Research Centre General Hospital, Pasighat, wer...