UNLABELLED The purpose of this study was to estimate the fetal radiation exposure resulting from (18)F-FDG PET procedures performed in pregnant patients with malignancies. METHODS Five pregnant patients with a biopsy-proven diagnosis of malignancy who underwent (18)F-FDG PET studies were retrospectively reviewed. All patients underwent PET-only studies (and not PET/CT studies) with a reduced ...

Linoleic acid plasma kinetics in pregnant baboons and its conversion to long chain polyunsaturates (LCP) in fetal organs is characterized over a 29-day period using stable isotope tracers. Pregnant baboons consumed an LCP-free diet and received [U-13C]linoleic acid (18:2*) in their third trimester of gestation. In maternal plasma, 18:2* dropped to near baseline by 14 days post-dose, while label...

The purpose of this study was to characterize the disposition of zidovudine in the maternal-fetal-amniotic fluid unit in vivo. Zidovudine was administered as a constant-rate infusion or a bolus dose to the dam, fetus and amniotic cavity (bolus dose only) of the near-term pigtailed macaque model. A fetal-maternal plasma steady-state concentration ratio of 0.76 +/- 0.06 suggested that the drug wa...

OBJECTIVE: To give a comprehensive overview of fetal doses reported in the literature when imaging the pregnant woman with suspected pulmonary embolism (PE). METHODS: A comprehensive literature search in the PubMed, MEDLINE and EMBASE databases yielded a total of 1,687 papers that were included in the analysis and have been analysed with regard to fetal dose in suspected PE radiological imagin...

To study the protective effects of maternal thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in congenital hypothyroidism, we gave pregnant rats methimazole (MMI), an antithyroid drug that crosses the placenta, and infused them with three different doses of T4 or T3. The concentrations of both T4 and T3 were determined in maternal and fetal plasma and tissues (obtained near term) by specific RIA...

This work aims to determine whether lead shielding can be used to decrease the radiation dose to the fetus during CT scans for the diagnosis of pulmonary embolism during early stage pregnancy. An anthropomorphic phantom was modified to contain a 15 cc ionization chamber at the site of the uterus to enable fetal dose to be measured. The effects of a range of scan parameters, positioning of lead ...

Abstract Background The current study was carried out to investigate the effects of exogenous progesterone on fetal development in rats. Results Placental weights did not vary control and treated groups. Fetal were significantly reduced low- high-dose CVL both treatment groups compared group. In fetuses that received maternal with progesterone, several parts skeleton showed incomplete ossificat...

In certain situations where there is a risk of fetal-pelvis disproportion (risk that the baby will not be able to pass through pelvis), pelvic scan examination may prescribed mother at end pregnancy. This assesses dimensions pelvis by measuring various bone diameters. It also provides details information about morphology. Patients are routinely worried unwanted effects on fetus from radiation e...