Effect of hexane extract of Ferula jaeschkeana has been studied on the histological and biochemical constituents of the uterus of ovariectomized rats. Its administration caused remarkable increase in the height of luminal epithelium and the number of uterine glands. Its per se treatment also caused significant increase in the glycogen and protein contents and the activity of acid and alkaline p...

Seventeen daucane sesquiterpenoid esters, including a new one (4), were isolated from the root of Ferula hermonis Boiss. The structures of the isolated compounds were elucidated on the basis of spectroscopic evidence and correlated with known compounds. The relative stereochemistry of the new compound was determined using 2D NOESY and the most stable and the lowest energy conformation was deter...

The medicinal plant Ferula has been widely used in Asian medicine, especially in Uyghur medicine in Xinjiang, China. Given that various substitutes and closely related species have similar morphological characteristics, Ferula is difficult to distinguish based on morphology alone, thereby causing confusion and threatening the safe use of Ferula. In this study, internal transcribed spacer 2 (ITS...

ferula gummosa boiss is a good source of biologically active compounds such as monoterpene and sesquiterpene derivatives. there are also several reports on antioxidant effects of these compounds. the aim of this study was to investigate the effect of daily administration of f. gummosa root hydro-alcoholic extract on serum oxidant-antioxidant status. twenty four wistar rats were randomly divided...

background and objectives: acinetobacter spp. are important causes of nosocomial infections. they possess various antibiotic resistance mechanisms including extended spectrum beta lactamases (esbls). the aim of this study was to determine antibiotic resistance profile of acinetobacter clinical isolates especially among esbl-producing strains and to investigate the antimicrobial effects of oleo-...

conclusion according to our findings, it is recommended to use ferula gummosa extract, as a herbal alternative treatment, in more investigations to prove its treatment effects on infections. objective ferula gummosa grows as a native plant in different parts of iran and has been used for treatment of some infections such as uti since ancient times. present study is planned to show the antibacte...

the fruit essential oil of ferula gummosa boiss., umbelliferae, which has been used as an antiepileptic remedy in iranian traditional medicine, was evaluated for anticonvulsant activity against experimental seizures. the essential oil had no effect against seizures induced by maximal electroshock. however, it protected mice against pentylenetetrazole-induced tonic seizures. the protective dose ...

in iranian traditional medicine, there are some report regarding the anticonvulsant effect of ferula gummosa boiss. in this study, anticonvulsant activity, neurological deficits and lethality of the root acetone extract of this plant were evaluated in mice. the extract exhibited dose-dependent prevention of tonic seizures induced by pentylenetetrazole (ed50 = 154.4 mg/kg). however, the extract ...