Following a pulse with 59Fe-transferrin, K562 erythroleukemia cells incorporate a significant amount of 59Fe into ferritin. Conditions or manipulations which alter the supply of iron to cells result in changes in the rate of ferritin biosynthesis with consequent variations in the size of the ferritin pool. Overnight exposure to iron donors such as diferric transferrin or hemin increases the fer...

Abstract Background Prevention of myocardial siderosis is a key step to reduce rate of mortality in thalassemic patients. Our objective was to study association between echocardiography parameters and serum ferritin level in patients with major thalassemia. Materials and Methods Sixty-six patients with major thalassemia were studied in Amir Kabir hospital, Arak, Iran. Serum ferritin levels ...

Background: Beta-thalassemia major is a type of inherited blood disease that results in variable outcomes such as severe anemia due to haemoglobin chains. Recurrent and lifelong blood transfusions as a treatment in beta-thalassemia major disease lead to iron deposition in various organs and cause the failure of multiple organs. Failure of affected organs leads to Body mass index (BMI) abnormali...

Urinary ferritin levels were measured by a "2-site" immunoradiometric assay in normal volunteers and in patients with various hematologic disorders. The mean urinary ferritin concentration in normal subjects averaged 2.2 microgram/liter, only 3% of the serum ferritin level. Elevated urinary ferritin levels averaging 45 microgram/liter were observed in patients with hematologic malignancies, but...

background: increased estimated body iron stores have been recently suggested to be associated with increased risk of acute myocardial infarction (ami); however the question of whether serum ferritin level as an indicator for estimating body iron is an independent risk factor for cardiac events is still questioned. in the present study, we assessed whether serum ferritin was associated with the...

To develop a method for the early diagnosis of health damage due to arc welding, we measured serum ferritin in 96 general employees and 320 arc welders in Company A. A positive correlation was observed between age and the serum ferritin level in the young group (age, 20 44 years) among the general employees. The mean serum ferritin level in the general employees was 119 ± 56 ng/ml. When the mea...

introduction: elevated levels of crp are present among patients at risk for further first-ever myocardial infarction and stroke. it has been shown that after ischemic stroke, increased levels of crp are associated with unfavorable outcomes. methods: from 120 patients admitted to the emergency unit of our hospital with the diagnosis of stroke crp, d-dimer and ferritin level was measured and the ...

ferritin is a macromolecule and is responsible for the long term iron storage function in human serum and plasma. recent studies have highlighted the role of cell phone exposure on central nervous system, immune function and reproduction. the aim of this study was to investigate whether the human serum ferritin level could be interfered by the exposure to the 900 mhz gsm cell phones. fifty huma...