In this study, a method for extraction and preconcentration of trace amounts of organophosphorus pesticides (OPPs) in environmental water using magnetic solid phase extraction (magnetic-SPE) followed by high performance liquid chromatography (HPLC) with UV detection was developed. The magnetic carbon nanotube adsorbents (Fe3O4/CNT) were synthesized by grafting carbo...

Fenitrothion, endosulfan and abamectin are insecticides that affect various organs in humans and animals. The present study was conducted to investigate their cytotoxicity in isolated male rat hepatocytes. The study suggests that incubation of hepatocytes with 10 or 100 microM of each insecticide for 2h significantly decreased the cell viability. Increased leakage percentage of lactate dehydrog...

A sensitive biosensor based on acetylcholinesterase (AChE) and carbon nanosphere (CNS) immobilized on a glassy carbon electrode was developed for the detection of pesticides by the inhibition of AChE activity. The inhibition effect of the pesticides resulted in a decrease of current response of the acetylthiocholine chloride that was used as a substrate to obtain an electrochemical signal. When...

The ability of targeted and nontargeted metabolomics to discover chronic ecotoxicological effects is largely unexplored. Fenitrothion, an organophosphate pesticide, is categorized as a "red list" pollutant, being particularly hazardous to aquatic life. It acts primarily as a cholinesterase inhibitor, but evidence suggests it can also act as an androgen receptor antagonist. Whole-organism fenitr...

Insecticidal properties of fenitrothion microcapsules (MC3) as a new residual spraying formulation for mosquito control were studied. Adult female Anopheles albimanus were confined so as to contact several surfaces treated with fenitrothion MC or wettable powder (WP) for 10 and 30 min. Residual efficacy of MC at the rate of 1 g/m2 was almost equivalent to that of WP at the rate of 2 g/m2 on a p...

OBJECTIVE The aim of the present study was to compare between two antioxidant treatments in prevention of fenitrothion induced toxicity on rat parotid salivary gland. DESIGN Forty adult male Wistar rats with an average weight of 120-150 g were randomised into 4 groups, control (group I), fenitrothion administration (group II), fenitrothion administration 1h after green tea extract or Nigella ...

Phosphorothioate insecticides, such as fenitrothion, are suicide substrates of cytochromes P450 (P450). These compounds undergo oxidative desulfuration by P450 resulting in the release and subsequent binding of atomic sulfur to the enzyme. Consequently, the P450-dependent metabolism of certain endogenous substrates could be inhibited by exposure to these insecticides. Formation of 2-hydroxyestr...

investigation on the current response of an.stephensi larvae to four who recommended larvicides, i.e. malathion, temephos, chlorpyrifos and fenitrothion, were carried out in the laboratory in 1999. diagnostic concentrations of pesticides only yielded 100% mortality with malathion. in contrast, levels of susceptibility to temphos, chlorpyrifos (0.025 mg/l) and temephos (0.625 mg/l) killed 72%, 9...