lung (an increase in forced VC). Dr. Petty’s preference to use the FEV1/FVC ratio is wellunderstood. It has been well-described that subjects with airway obstruction, that is, a low FEV1/FVC ratio, are more likely to have airway hyperresponsiveness (AHR). We evaluated the association between the “new” ratio (ie, FEF25–75/FVC) and AHR because we believed that it describes a potentially different...

Disease exacerbations are an important aspect of COPD, because they affect its course and are associated with higher lung function decline. On the other hand, data obtained by biopsies have demonstrated that the progression of COPD is related to an increasing impairment of small airways. We sought to evaluate the small airway impairment (FEF25-75) in two groups of COPD patients (each group had ...

BACKGROUND The aim of this study was to assess the early postoperative pulmonary function and arterial blood gases in patients who have undergone open versus laparoscopic nephrectomy. MATERIALS AND METHODS Forty patients were randomly assigned to undergo laparoscopic (LN, n=20) or open nephrectomy (ON, n=20). Pulmonary function tests including forced expiratory volume in 1 second (FEV1), forc...

Objective: To determine the cut-off points for FEV1, FEV0.75, FEV0.5, and FEF25-75% bronchodilator responses in healthy preschool children and to generate reference values for FEV0.75. Methods: This was a cross-sectional community-based study involving children 3-5 years of age. Healthy preschool children were selected by a standardized questionnaire. Spirometry was performed before and after...

BACKGROUND Chronic obstructive pulmonary disease is a global problem and available data from sub-Saharan Africa is very limited. METHODS A cross-sectional facility-based pilot study among patients and visitors to an urban and a rural primary healthcare facility was conducted in coastal Tanzania. The primary outcome was the prevalence of chronic airflow obstruction. RESULTS The final analysi...

Two samples of a manual 3 L calibrating syringe which displays an electronically calculated FEF25-75% were evaluated to determine its suitability as a flow calibrator were evaluated. Room air was discharged into a manual spirometer system known to be accurate. The calibrator-determined values correlated very closely with the spirometer values over an FEF25-75 % range of 0.4 to 9 L/sec. The diff...

84 http://e-aair.org Jang and colleagues investigated the relationship between exhaled nitric oxide (FeNO) and atopy profiles in children with asthma. They focused their attention mainly on the FeNO, showing that this parameter varied according to the profile of atopy. The authors also investigated lung function, including bronchial hyperreactivity. However, forced vital capacity, forced expira...

BACKGROUND Total lung capacity (TLC), forced expiratory flow between 25 and 75% (FEF25-75%), peak expiratory flow (PEF), or post-bronchodilator volume response is recommended to detect obstructive abnormalities in the lung. The present study was performed to evaluate the usefulness of these pulmonary function test (PFT) parameters to diagnose obstructive lung disease in subjects with a restrict...

BACKGROUND Previous studies have shown conflicting results for the association between TLR4 polymorphism (Asp299Gly) and lung function. We investigated the influence of TLR4 Asp299Gly, a polymorphism, on lung function in a community population. METHODS In 2003, a cross-sectional survey was conducted to assess the respiratory health of residents living in and around the town of Humboldt, Saska...