Microorganisms are constantly exposed to rapidly changing conditions, under natural as well as industrial production scale environments, especially due to large-scale substrate mixing limitations. In this work, we present an experimental approach based on a dynamic feast/famine regime (400 s) that leads to repetitive cycles with moderate changes in substrate availability in an aerobic glucose c...

G Kahen, M M Lehman and J F Ramil Department of Computing Imperial College London SW7 2BZ tel: +44 (0)171 594 8216 fax: +44 (0)171 594 8215 {gk,mml,ramil}@doc.ic.ac.uk http://www-dse.doc.ic.ac.uk/projects/feast The Global Software Process The FEAST hypothesis [leh94] and the nature and results of the FEAST/1 study have been widely disseminated in the last three years, as may be seen from examin...

Feast and famine cycles are common in activated sludge wastewater treatment systems, and they select for bacteria that accumulate storage compounds, such as poly-beta-hydroxybutyrate (PHB). Previous studies have shown that variations in influent substrate concentrations force bacteria to accumulate high levels of rRNA compared to the levels in bacteria grown in chemostats. Therefore, it can be ...

The process of E-type software development and evolution has proven most difficult to improve, possibly due to the fact that the process is a multi-input, multi-output system involving feedback at many levels. This observation, first recorded in the early 70s during an extended study of OS/360 evolution, was recently captured in a FEAST hypothesis; a hypothesis being studied in on-going twoyear...

Feast-famine cycles in biological wastewater resource recovery systems select for bacterial species that accumulate intracellular storage compounds such as poly-β-hydroxybutyrate (PHB), glycogen, and triacylglycerols (TAG). These species survive better the famine phase and resume rapid substrate uptake at the beginning of the feast phase faster than microorganisms unable to accumulate storage. ...

Three FEAST workshops were held at Imperial College during 1994/5 [fea94/5] to explore the FEAST hypothesis, itself formulated in 1993 [leh94]. The FEAST/1 project (1996-8) [leh95] funded by EPSRC followed and led, in turn, to FEAST/2 (1999-2001) [leh98]. Many of the results of these studies have been published over the past few years. They may be found on the FEAST web site at As part of their...

In the context of a hypothesis attributing the slow progress in achieving major global software process improvement, in part, to overlooking the role of feedback in that process, the FEAST/1 project is studying the impact of feedback on software evolution. Amongst its activities the project is analysing metrics of the evolution of several industrial systems, ranging from a financial transaction...