We characterized Fc receptor III (FcR III) on human neutrophils and found it to be heavily glycosylated and polymorphic. In some individuals, FcR III that had been digested with N-glycanase appeared after SDS-PAGE under reducing conditions as two bands with apparent molecular masses of 33 and 29 kD. In other individuals, N-glycanase-treated FcR III appeared as a single band with an Mr of either...

IgG-FcR+-T cell ratio was measured in 50 patients with bladder tumor as a parameter to estimate the cell mediated immunity before the treatment. IgG-FcR+-T cell was detected by the double rosette method, employing sheep erythrocytes and rabbit IgG antibody coated chicken erythrocytes. IgG-FcR+-T cell ratio in 50 patients with bladder tumor was 7.6 +/- 5.7% (mean +/- standard deviation), while t...

Interaction between von Willebrand factor (vWF) and glycoprotein Ib (GPIb) stimulates tyrosine kinases and subsequent tyrosine phosphorylation events in human platelets. This study found that the combination of vWF and botrocetin, by interacting with GPIb, induced tyrosine phosphorylation of Fc receptor gamma-chain (FcR gamma-chain), Syk, linker for activation of T cells (LAT), and phospholipas...

BACKGROUND AND OBJECTIVES The American Academy of Pediatrics recommends family-centered rounds (FCR) as standard practice for the inpatient setting. To date, there is limited research investigating the attitudes of pediatric patients regarding this shift in practice. The goal of this study was to explore pediatric patients' perspectives of their experiences during FCR. METHODS We conducted a ...

After infection with bacillus Calmette-Guérin, peritoneal macrophages (Mø) display enhanced expression of FcR for both monomeric and complexed IgG2a, but not IgG2b. Isotype specificity of FcR can be reversed on nonactivated Mø by immune lymphokines, and IgG2a immune complexes are more effective triggers of the respiratory burst in activated Mø. Selective enhancement of IgG2a FcR by Mø activatio...

We investigated the effect of selection for 4-wk feed conversion ratio (FCR) on genetic improvement of FCR, BW, weight gain (WG), feed intake (FI), and residual FI (RFI) in Japanese quail. The F line was selected for reduced FCR and the C line was maintained as a randombred control. In each generation, 35 sires and 70 dams were used as parents for the next generation. Three generations of selec...

PURPOSE A new processing parameter (T-type parameter) setting for gray scale was developed to improve the image quality of digital mammograms. To clarify the usefulness of this parameter setting, we have evaluated the image quality of digital mammograms (hard copy images) processed with this parameter, and compared it with S/F mammography. MATERIAL AND METHODS Mammograms were made under the s...

BACKGROUND Family-centered rounds (FCR) are defined as interdisciplinary bedside teaching rounds with active family participation. The objective of this study was to examine the association of FCR with family experiences and health services use. METHODS Prospective study comparing families with a child admitted to general pediatric inpatient services with and without FCR. The presence of FCR ...

While it is generally accepted that most B lymphocytes express Fe-receptors (FcR) (1), 1 evidence for the expression of FcR by T cells is controversial. Thus, while some works have claimed that a high proportion of thymus cells display FcR (2), others have failed to demonstrate FcR on these cells (1). FcR, however, could be detected on several murine T cell lymphomas (2, 3, and footnote 2), and...

Although fludarabine, cyclophosphamide, and rituximab (FCR) together are established as a standard first-line treatment of younger patients with chronic lymphocytic leukemia (CLL), there is little information to guide the management of patients with CLL refractory to, or who have relapsed after, receiving frontline FCR treatment. To define optimal salvage strategy and identify patients unsuitab...