In Europe G6PD deficiency is encountered most frequently in Sardinia and Greece but may also be found in other Mediterranean countries (Sansone, Piga, and Segni, 1958; Szeinberg, Asher, and Sheba, 1958), including Yugoslavia (Fraser, Grunwald, and Stamatoyannopoulos, 1966). The occurrence of haemolytic anaemia after ingestion of fava beans in Yugoslavia was first reported as a clinical finding ...

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common hereditary enzyme disorder and more than 200 million people have a deficiency in this enzyme. It is a globally important cause of neonatal jaundice and causes life-threatening hemolytic crisis in childhood. At later ages, certain drugs such as antimalarials, and fava beans cause hemolysis among G6PD deficiency patients. The ...

In order to investigate the heavy metal contamination of soil-crop in mining-intensive areas Gejiu stannary Yunnan Province and its risk human health, single-factor index method Nemero comprehensive were used evaluate metals (Cd As) soil areas, health evaluation model was study brought by residents through consumption maize, wheat broad beans. The results showed that mean values total As Cd are...

BACKGROUND Favism occurs as the result of intolerance to the ingesting of fava beans or to the inhalation of pollen from the Vicia faba plant. Patients with favism are always Glucose-6-phosphate dehydrogenase (G6PD)-deficient, but not all G6PD-deficient individuals develop hemolysis as a result of fava beans consumption. PATIENTS AND METHODS Blood samples were collected from children with fav...

Faba beans (Vicia faba L.), also known as fava beans, like other crops, are influenced by several factors: their genotype, environment, and management, well the interaction between these, have an important impact on seed yielding quality traits. This study was conducted at three locations in South Italy 2017 2019 to evaluate sowing date effect yield components of Vicia L., originating from cool...

Favism is an acute hemolytic anemia known to occur in susceptible individuals who ingest fava beans. Susceptibility to favism is conferred by a genetic deficiency in erythrocytic glucose-6-phosphate dehydrogenase (G6PD) activity. Although the fava bean pyrimidine aglycones, divicine and isouramil, have been implicated in the onset of favism in humans, the lack of a well-defined experimental ani...

Favism is an acute anemic crisis that can occur in susceptible individuals who ingest fava beans. The fava bean pyrimidine aglycone divicine has been identified as a hemotoxic constituent; however, its mechanism of toxicity remains unknown. We have shown recently that divicine can induce a favic-like response in rats and that divicine is directly toxic to rat red cells. In the present study, we...