materials and methods in this case-control study, using the polymerase chain reaction (pcr), adrs266729 and rs2241766 gene polymorphisms were genotyped in b-type ultrasonography-proven nafld patients, with (n = 246) or without (n = 247) cad and in healthy controls (n = 304). serum lipid profiles were determined using biochemical methods. statistical analyses were performed using spss 17.0 stati...

non-alcoholic fatty liver disease (nafld) is the leading cause of chronic liver disease in the united states and other industrialized countries, and the reported prevalence in the developing countries is also rather high. this disease is associated with a high rate of morbidity and mortality and damage to the other organs. the cardiovascular system is, perhaps, the most vulnerable organ to nafl...

background: obesity may lead to various morbidity including liver diseases. the present study was done to determine which obesity indices, including body mass index (bmi), waist circumference (wc), waist to hip ratio (whr), and waist to height ratio (whtr) have the stronger association with rising levels of alanine aminotransferase (alt). material and methods: of 6143 subjects aged ≥ 10 years o...

background: polycystic ovary syndrome (pcos) is highly associated with non-alcoholic fatty liver disease (nafld). there are extensive ethnic differences in the clinical manifestations, pathological changes, and ovarian changes in women with pcos. objective: to investigate the prevalence and clinical characteristics of nafld in chinese women with pcos. materials and methods: non-pregnant women w...

background: nonalcoholic fatty liver disease (nafld) is the most common cause of chronic liver disease in the world. although some studies have been conducted about dietary intakes of these patients, but the results are inconsistent. the aim of this study was to survey all macronutrients and micronutrients included in dietary intake of these patients for better understanding the factors influen...

conclusions we confirmed that serum opg concentrations reduce in obese children. however, no correlation was identified between opg and insulin resistance. opg levels are not meaningful in the diagnosis of nafld in children with obesity. methods this was a prospective, cross-sectional, controlled study that was conducted in the department of pediatrics at bagcilar training and research hospital...

we evaluated the effect of vitamin e and metformin on fatty liver disease in obese children.this interventional study has been done on 119 children with non-alcoholic fatty liver disease (based on sonography results). patients were divided into four treatment groups; they received metformin 1gr daily (age 12 years), vitamin e 800 u daily and vitamin e 400 u daily. liver sonography was performed...

background: the aim of this study was to assess the association between insulin resistance, metabolic syndrome and nonalcoholic fatty liver disease (nafld) in chinese adults. methods: fifty five subjects with nafld and 55 controls were enrolled for the study. waist circumference, blood pressure, plasma triglyceride, high density lipoprotein cholesterol and fasting plasma glucose concentrations ...

background genome-wide association studies have shown that rs738491, rs2143571, and rs3761472 in the sorting and assembly machinery component 50 homolog (samm50) gene are significantly associated with susceptibility to nonalcoholic fatty liver disease (nafld). conclusions we first demonstrated that the rs738491 t allele, rs2143571 a allele, and rs3761472 g allele in the samm50 gene created susc...