Objective—To examine the relation between fatigue, disease activity, damage, and quality of life measures in patients with systemic lupus erythematosus (SLE). Methods—Consecutive patients attending the University of Toronto Lupus Clinic were studied. Disease activity was assessed using the SLEDAI and SLAM-R and damage using the SLICC/ACR Damage index. Fatigue was measured by the Fatigue Severit...

This paper presents the concept and architecture of a fatigue damage control system for mechanical structures. In contrast to the conventional cycle-based approach, fatigue damage is represented via non-linear differential equations with respect to time in the state-variable setting. This damage model is compatible with the dynamic model of the plant, i.e. the process under operation and contro...

Keywords: Damage equivalence factors Fatigue load model Equivalent length Weigh-In-Motion Traffic load model Monte-Carlo simulation a b s t r a c t The fatigue design of bridges under variable amplitude traffic loads is not straightforward. To simplify the task, the current Eurocode provisions apply fatigue load model 3 and damage equivalence factors (k). However , the fatigue load model and th...

A new model for fatigue damage evolution of polymer matrix composites is presented. The model is based on a combination of an orthotropic damage model and an isotropic fatigue evolution model. The orthotropic damage model is used to predict the orthotropic damage evolution within a single cycle. The isotropic fatigue model is used to predict the magnitude of fatigue damage accumulated as a func...

PURPOSE Fourteen male cyclists were studied to compare the effect of carbohydrate-protein-antioxidant beverage (CHOPA) to an isocaloric carbohydrate-only (CHO) beverage on time to fatigue and muscle damage. METHODS Subjects performed two sets of rides to exhaustion on a cycle ergometer. In each set, the first ride was performed at 70% VO2peak, and the second was performed 24 h later at 80%. C...