The fat embolism syndrome, often a complication of major trauma, frequently passes undiagnosed. The classical picture of cerebral confusion, respiratory distress and petechiae of skin and mucosa is not always seen. A distinction must be made between the clinical entity and fat embolism demonstrated pathologically. Post-mortem, fat embolism is often found after deaths from causes other than trau...

Fat embolism occurs in the vast majority of patients who have had trauma (approximately 90%). The most common occurrence is after long bone fracture. It has also been noted in cases after orthopedic surgery. Fat embolism is most often diagnosed when the clinical manifestations of fat embolism syndrome become apparent. Reported cases of fat emboli in transit are unusual. In our case, we present ...

Nearly all long-bone fractures are accompanied by some form of fat embolism. The rare complication of clinically significant fat embolism syndrome, however, occurs in only 0.9-2.2% of cases. The clinical triad of fat embolism syndrome consists of respiratory distress, altered mental status, and petechial rash. Cerebral fat embolism causes the neurologic involvement seen in fat embolism syndrome...

Fat embolism syndrome is a clinical diagnosis, and diagnostic procedures are not specific. In every trauma patient, Fat embolism syndrome has to be considered as a possibility and supportive treatment should begin as soon as possible. The authors reported a rare case of Fat embolism syndrome whose only neurological symptom was motor aphasia. A young man sustained comminuted femoral shaft fractu...

Fat embolism syndrome refers to a constellation of symptoms secondary to the presence of fat globules in the lung parenchyma and/or peripheral blood circulation. The syndrome is most often seen in association with long bone or pelvic fractures and can cause significant morbidity and mortality. The present randomized double blind placebo-controlled trial was conducted to evaluate the efficacy of...

Cerebral fat embolism syndrome (CFES) is a neurologic syndrome occurring in up to 60% of patients with fat embolism syndrome (FES). The defining features of FES include respiratory, neurologic and dermatologic features. The classical explanation is release of fat emboli into the circulation after long bone fractures, but the clinical syndrome of FES only occurs in 0.5-3% of cases, typically wit...

Fat embolism syndrome (FES) has been recognized for more than 100 years, but controversy remains with regard to the mechanism of systemic fat embolism. We report a case of healthy 30-years-old men who developed respiratory failure and brain death within 48 h of bilateral tibial fractures. Autopsy showed fat embolism in the lung and brain, and a large patent oval foramen that may have contribute...

Duchenne muscular dystrophy is the most frequent lethal genetic disease. Several clinical trials have established both the beneficial effect of steroids in Duchenne muscular dystrophy and the well-known risk of side effects associated with their daily use. For many years it has been known that steroids associated with ambulation loss lead to obesity and also damage the bone structure resulting ...