conclusion statistical analysis of susceptibilities of ms patients versus healthy subjects found no excess deposition of calcium content in deep gray matter of ms patients. calcification may not be considered as a biomarker of prognosis in ms. results magnetic susceptibility(x) of calcium content was assessed by number of pixels induced by gp and put in ms patients as well as healthy subjects. ...

Primary familial brain calcification (PFBC), also referred to as Idiopathic Basal Ganglia Calcification (IBGC) or "Fahr's disease," is a clinical condition characterized by symmetric and bilateral calcification of globus pallidus and also basal ganglions, cerebellar nuclei, and other deep cortical structures. It could be accompanied by parathyroid disorder and other metabolic disturbances. The ...

ABSTRACT: Hypoparathyroidism refers to a group of disorders in which extracellular calcium levels cannot be maintained within the normal range due to relative or absolute deficiency of parathyroid hormone. Clinically, hypoparathyroidism manifests predominantly as neuromuscular dysfunction caused by hypocalcemia. Basal ganglia calcification in particular is associated with hypoparathyroidism. Tw...

There is a growing interest in defining the genetic background of autosomally dominant inherited Familial Idiopathic Basal Ganglia Calcification (FIBGC), a neuropsychiatric condition often described as ‘‘Fahr’s Disease’’ [1–3]. However, the current debate about the nosology of this heterogeneous phenotype demands a search for standard diagnostic criteria and the identification of loci or mutati...