abstract       background and objectives: plasmodium falciparum merozoite surface protein-1 (pfmsp-1) is a promising vaccine against malaria during its blood stages which play an important role in immunity to this disease. polymorphic nature of this gene is a major obstacle in making an effective vaccine against malaria. in this study, the genetic diversity of plasmodium falciparum isolates was...

circumsporozoite protein (csp) is one of the stage specific antigens, which is used for the development of vaccines and to investigate the genetic diversity in plasmodium falciparum malaria parasite. polymerase chain reaction was used for typing of csp genes on 67 positive falciparum malaria patients from sistan and baluchistan province of iran. three fragments were detected for csp gene. twent...

malaria is a parasitic disease that is starting to be encountered in intensive care units (icu) worldwide, owing to increasing globalisation. severe malaria caused by plasmodium falciparum , is characterised by cerebral malaria, acute renal failure, hypoglycaemia, severe anaemia, splenomegaly and alveolar oedema. we present the case of a 25-yr old male patient who presented to the emergency dep...

according to willingness of the ministry of health, iran and presence of appropriate conditions for disease elimination, national malaria control program decided to conduct a research to clarify malaria status in 2007 and to provide required information to perform the elimination program. this review is comprised of the basis of national malaria elimination program in vision of 2025, which was ...

We conducted this study to determine if the finding of schizontemia could be used as an indicator of severe falciparum malaria. We enrolled 250 patients with severe falciparum malaria and 250 patients with umcomplicated falciparum malaria into the study. Severe falciparum malaria was defined following World Health Organization criteria (2010). Of the 250 patients with severe falciparum malaria,...

mixed malaria infections, plasmodium falciparum and p. vivax, are suspected to occur at a greater frequency than is detected by conventional light microscopy. in order to determine the year round pattern of transmission and the frequency of mixed infections in malaria endemic area, we carried out a prospective comparison of diagnosis by conventional light microscopy and nested pcr in chahbahar ...

malaria had being widely prevalent for a long time in iran. before starting any anti-malarial campaign in iran about 60% of population was living in malaria endemic areas. in hyper-endemic areas, approximately 30 to 40% of the total mortality was due to malaria. the malariometric data, reported during 1921-1949 in the malaria surveys in some endemic areas, showed high endemicities of the diseas...

Malaria is a major public health problem in India. India’s varied geography and diverse climatic conditions from tropical monsoon the south to temperate north, favor distribution of vectors species malaria parasite. India takes several forms, including forest/ tribal malaria, urban industrial plains malaria. P. falciparum P vivax contribute majority malarial cases deaths