One of the biggest challenges facing modern computer architects is overcoming the memory wall Technology trends dictate that the gap between processor and memory performance is widening Even though good cache behavior mitigates this problem to some extent memory latency remains a critical performance bottleneck in modern high performance processors Al though current high speed systems have impr...

Measuring the quality of metadata is only possible by assessing the quality of the underlying schema and the metadata instance. We propose some factors that are measurable automatically for metadata according to the CMD framework, taking into account the variability of schemas that can be defined in this framework. The factors include among others the number of elements, the (re-)use of reusabl...

This paper presents the first systematic comparison between south-facing monofacial and bifacial photovoltaic (PV) modules, as well vertical east-west facing PV modules in Alaska. The state’s solar industry, driven by high price of energy dropping equipment costs, is quickly growing. challenges posed extreme sun angles Alaska’s northern regions also present opportunities for unique system desig...

We study a hybrid strategy that uses both process flexibility and inventory to mitigate risks of plant disruption. In this setting, a firm allocates inventory before disruption while facing demand uncertainties; demand is realized after disruption, and the firm schedules its production using process flexibility to minimize lost sales. This interplay between process flexibility and inventory is ...

This paper presents a new wind speed measurement method using a single capacitive micro-machined ultrasonic transducer (CMUT). The CMUT was arranged perpendicular to the direction of the wind flow, and a reflector was set up a short distance away, facing the CMUT. To reduce the size, weight, cost, and power consumption of conventional ultrasonic anemometers this study proposes two CMUT designs ...

The memory and storage system, including processor caches, main memory, and storage, is an important component of various computer systems. The memory hierarchy is becoming a fundamental performance and energy bottleneck, due to the widening gap between the increasing bandwidth and energy demands of modern applications and the limited performance and energy efficiency provided by traditional me...

Microfabricated impedance cytometers have been developed to measure the electrical impedance of single biological particles at high speed. A general approach to analytically solve the electric field distributions for two different designs of cytometers: parallel facing electrodes and coplanar electrodes, using the Schwarz-Christoffel Mapping method is presented. Compared to previous analytical ...

The key to writing high quality parallel software is to develop a robust software design. This applies to the overall architecture of the program, but also to the lower layers in the software system where the concurrency and how it is expressed in the final program is defined. Technology to more systematically describe such designs and reuse them between software projects is the fundamental pro...

This white paper discusses current methods for assessing nAb responses and defining genetic determinants of neutralization escape. It also describes the breadth and potency of nAb responses elicited during HIV infection and the primary challenges facing the development of a broadly protective vaccine. Finally, it shares recent efforts to generate new broadly neutralizing monoclonal antibodies (...