The purpose of a classification is not only to group diseases with the same biological characteristics, but also to get insight into the pathogenesis and to define subgroups with different prognoses and different therapeutic approaches. In acute leukaemias the classification now most widely used is the French-American-British (FAB) classification as proposed in 1976, which was based on morpholo...

Acute myeloid leukemia (AML) should be classified into subtypes according to the French-American-British (FAB) or, preferably, the newer World Health Organization (WHO) classification schemes. FAB is purely a morphological classification. It does not determine treatment (except M3) or prognosis for the patient which requires cytogenetics. Haematological analyzer had been used for classification...

The French-American and British (FAB) classification of 62 consecutive cases of acute myeloid leukemia was undertaken. AML-M2 was the commonest FAB type (32.26%), followed by M1 and M4 (22.58% each), M5 (8.6%) and M6 and M7 (1.61% each), respectively. One of the patients was diagnosed as AML-MO (not a FAB type). The mean age of M1, M2, M3 and M5 cases was between 25 and 29 years, whereas in M4 ...

AIMS To analyse the forward scatter/side scatter (FSC/SSC) distribution of acute myeloblastic leukaemia (AML) blast cells in order to assess whether it correlates with their morphology, immunophenotype, and clinical and biological disease characteristics. METHODS FSC/SSC patterns were established upon taking into account the localisation of the residual T lymphocytes in the FSC/SSC dot plot a...

Our expanding knowledge of acute myeloid leukemia (AML) over the last four decades has resulted in major advances in the understanding and classification of this disease. What we consider as acute myeloid leukemia is now known to represent a number of distinct, but related diseases, some of which require unique therapeutic approaches. The World Health Organization (WHO) classification of AML at...

A murine monoclonal antibody against human lysozyme (AHL MoAb) was produced and tested on normal and leukemic monocytes using flow cytometry. The antibody gave a positive reactivity on normal monocytes permeabilized by saponin (82% to 98% of positive cells) and a negative reactivity on normal permeabilized neutrophils. This monocyte-specific reactivity had not been observed using a polyclonal a...

background: cognitive impairment in patients with parkinson’s disease (pd) mainly involves executive function (ef). the frontal assessment battery (fab) is an efficient tool for the assessment of efs. the aims of this study were to determine the validity and reliability of the psychometric properties of the persian version of fab and assess its correlation with formal measures of efs to provide...

Output time prediction is a critical task to a wafer fab (fabrication plant). To further enhance the accuracy of wafer lot output time prediction, the concept of input classification is applied to Chen’s fuzzy back propagation network (FBPN) in this study by pre-classifying input examples with the self-organization map (SOM) classifier before they are fed into the FBPN. Examples belonging to di...

To further enhance the accuracy of lot output time prediction in a wafer fab (fabrication plant), a hybrid artificial neural network is proposed in this study. At first, the concept of input classification is applied to Chen’s fuzzy back propagation network (FBPN) by pre-classifying input examples with the self-organization map (SOM) classifier before they are fed into the FBPN. Then, examples ...