OBJECTIVE The study aimed to identify patient characteristics associated with differences in outcomes of acute treatment in day hospitals and conventional hospital wards. METHODS Data were from the European Day Hospital Evaluation (EDEN) (2000-2003), a multicenter randomized controlled trial comparing acute treatment in day hospitals and conventional wards in five European countries. All 880 ...

The negative effects of overexposure to ultraviolet (UV) radiation in humans, including sunburn and light-induced cellular injury, are of increasing public concern. 4-Methylbenzylidene camphor (4-MBC), an organic chemical UV filter, is an active ingredient in sunscreen products. To date, little information is available about its neurotoxicity during early vertebrate development. Zebrafish embry...

We evaluate the voluntary export restraint (VER) placed on Japanese automobile exports from 1977 to 1999 by the UK. We show that the policy failed to assist the British domestic car industry. Instead, UK-based US multinationals and Japanese manufacturers were the primary beneficiaries, at a substantial cost to UK consumers. While there are a number of caveats, the policy was on balance damaging...

Mechanisms implied in tissues response to the oxygen partial pressure remain poorly understood as well as the role of hypoxia in developmental processes. However, the activation of transcription factors such as FoxO and HIF and the recruitment of signalling pathways including Calcineurin, PI3K, p38-MAPK and mTOR are known to be involved in hypoxia responses. Currently, little information is kno...

The paper explores the insights offered by Marx’s analysis of the emergence of “world money” into the workings of the international gold standard period and the post-Bretton Woods floating dollar standard. In a curious inversion of the traditional formulations drawing on Lenin, imperial hegemony in today’s context would seem to be associated with net capital imports (rather than exports) by the...

about 60 percent of the world's known reserves of oil reside in the middle east region. as such, any developments of this region are of utmost importance for the world economy. the strait of hormuz is the export conduit for 90 percent of the oil of the countries bordering the persian gulf, supplying 40 percent of world oil consumption, and is controlled by our country. since assessment of ...

Trade, Peace and Democracy: An Analysis of Dyadic Dispute At least since 1750 when Baron de Montesquieu declared "peace is the natural effect of trade," a number of economists and political scientists espoused the notion that trade among nations leads to peace. Employing resources wisely to produce one commodity rather than employing them inefficiently to produce another is the foundation for c...

Adenosine A(2B) receptors are known as low-affinity receptors due to their modest-to-negligible affinity for adenosine and prototypic agonists. Despite numerous synthetic efforts, 5'-N-ethylcarboxamidoadenosine (NECA) still is the reference agonist, albeit nonselective for this receptor. In our search for higher affinity agonists, we developed decision schemes to select amino acids for mutation...