A multigeneration study with four successive generations of Syrian hamsters was conducted to determine whether a single s.c. injection of different doses of diethylnitrosamine (DEN) (1.25, 2.5, 5, 10, and 20 mg/kg body weight) on day 15 of pregnancy induces respiratory tract tumors not only in the treated P generation mothers and their F1 progeny but also in F2 and F3 generations. In this study...

aegilops triuncialis l. (2n=4x=28; ctctutut) is one of the tetraploid aegilops species harboring valuable genes for resistance to many biotic and abiotic stresses. in the present study the bread wheat cultivars mv17, navid, omid, pishgam, zarin were crossed with an accession of ae. triuncialis and the resulted f1 and f2 (obtained by the selfing of f1 plants) hybrids studied using the convention...

A developmental insult that restricts growth in the first generation has the potential to program disease in subsequent generations. The aim of this study was to ascertain transgenerational growth and cardio-renal effects, via the maternal line, in a rat model of utero-placental insufficiency. Bilateral uterine vessel ligation or sham surgery (offspring termed first generation; F1 Restricted an...

Zeugodacus cucurbitae is an important pest of fruit and vegetable crops in tropical subtropical regions, high-temperature stress can have different effects on the development reproduction successive generations Z. cucurbitae. To clarify multigenerational short-time high temperature cucurbitae, newly emerged adults contemporary (F1 generation) next generation (F2 were exposed to short-term tempe...

In order to investigate the genetic characteristics of soybean Leguminivora glycinivorella resistance and to improve soybean resistance insectivorous breeding efficiency by applying the multi-generation joint analysis method of the major gene plus polygene model, 5 pedigrees and generations (P1, F1, P2, F2, and F2:3) were used as the materials to perform the soybean L. glycinivorella resistance...

The effect of genotype, sex and hatch on carcass traits and physical characteristics of eggs was investigated in the Japanese quail. Two strains of Japanese quails including the White (P1) and Wild (P2) genotypes were chosen as the parental generation and crossed reciprocally (10 single-pair mating) to create the F1 progeny. The F1 birds (27 males and 81 females) were mated randomly to produce ...

Ancestral environmental exposures to a variety of environmental toxicants and other factors have been shown to promote the epigenetic transgenerational inheritance of adult onset disease. The current study examined the potential transgenerational actions of the herbicide atrazine. Atrazine is one of the most commonly used herbicides in the agricultural industry, in particular with corn and soy ...

OBJECTIVE Maternal undernutrition during gestation is associated with increased metabolic and cardiovascular disease in the offspring. We investigated whether these effects may persist in subsequent generations. DESIGN Historical cohort study. SETTING Interview during a clinic or home visit or by telephone. POPULATION Men and women born in the Wilhelmina Gasthuis in Amsterdam between Nove...

To create novel tomato (Solanum lycopersicum) germplasm, a wild relative, S. pimpinellifolium (a red-fruited LA1585 accession), was used as the male parent to cross with yellow-fruited mutant, e9292 (S. lycopersicum). Forty-four morphological characteristics were examined in present study; 22 (LA1585) traits and six lycopersicum (e9292) dominant hybrids (first generation, F1); 10 intermediate t...

Nonylphenol (NP) is a persistent environmental chemical that can disrupt the organism's endocrine system, and is detected in the surface water and sea. In this study, we investigated whether NP can alter transcriptional expression of sexual differentiation-related genes. Three generations of zebrafish were exposed to 0, 2, 20 and 200 μg·L-1 of NP, and transcriptional expression of sexual differ...