Intraocular melanomas, among the most com mon eye tumors in man, have seldom been reported in animals. This is particularly surprising in regard to the dog, a species that usually lives well into the "tumor age" and is affected by diverse neoplasms. In his "Pathology of Tumours" (1953) Willis (48) stated : ' 'I have not read of an intraocular melano ma in an animal." While reported cases are no...

Neoplasms and malignancies are seldom seen in the duodenum in comparison with other parts of the alimentary tract. Duodenal subepithelial lesions with umbilication are rare, often regarded typical for ectopic pancreas. Meanwhile, premalignant/ malignant transformation of ectopic gland might even be rarer. We present a case of a duodenal intraepithelial neoplasia, most likely originated from an ...

A total of 243 neoplasms were recorded in a survey of all the feline neoplasms which are reported in the registration files of the Veterinary Research Institute, Onderstepoort, Republic of South Africa, covering a 40-year period from 1935 to 1974. The tissues most commonly neoplastic were the skin, followed by the lymphoid tissue, the digestive tract and the genital system, which together accou...

PURPOSE To study the prevalence of multiple neoplasms in patients affected by uveal melanoma in Spain and to relate these with survival. METHOD We carried out a longitudinal prospective study of the prevalence of multiple neoplasms in patients diagnosed to have a uveal melanoma during the years 1984-2005. The data has been analysed for the following variables: age, sex, date of diagnosis, aff...

Choi, N. W . (Dept. Social and Preventive Medicine, Univ. of Manitoba, Winnipeg 3, Manitoba, Canada), L M. Schuman and W . H. Gullen. Epidemiology of primary central nervous system neoplasms. II. Case-control study. Amer. J. Epid., 1970, 97: 467-485.—This retrospective study was designed to elucidate selected epidemiologic variables possibly related to central nervous system (CNS) neoplasms. On...

Biallelic inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene predisposes human patients to the development of highly vascularized neoplasms in multiple organ systems. We show that zebrafish vhl mutants display a marked increase in blood vessel formation throughout the embryo, starting at 2 days post-fertilization. The most severe neovascularization is observed in distinct areas t...

Purpose: Ocular neoplasms, both primary and metastatic, may present with visual disturbance or vision loss often are asymptomatic. Clinical examination demonstrate leukocoria, abnormal pupillary light reflex, a mass lesion without retinal detachment hemorrhage. Retinoblastoma in children uveal melanoma ocular metastases adults the most important malignant neoplasms referred for imaging to aid d...

Nickel subsulfide, alpha Ni3S2, was administered to albino Fischer rats by a single injection into the vitreous body of the right eye (0.5 mg alpha Ni3S2/rat, suspended in 20 microliter of NaCl vehicle). Control rats received a similar injection of the vehicle. Malignant tumors developed in the injected eyes of 14/15 alpha Ni3S2-treated rats by 8 months (vs. 0/11 controls, p less than 0.001). F...

Orbital neoplasms with associated bone erosions and intracranial extension are generally considered suspicious for malignancies. Here, we describe the clinical and radiological findings, as well as the surgical management of two extraordinary cases, in which such bony perforations with subsequent intracranial tumor growth resulted from benign angiomatous orbital neoplasms. Two female patients, ...