abo blood type antigens are polymorphic, inherited structures presented on the surface of red blood cells. although abo blood group antigens is the most important antigens in transfusion medicine, its main role is not clearly clarified. correlation between abo blood group and susceptibility to certain infectious and non-infectious diseases is a controversial issue. since, lack of blood type ant...

background: molecules expressed on the surface of infected erythrocytes (ie) with plasmodium falci-parum play important roles in malaria pathogenesis and immune evasion. some of these molecules are specific adhesive ligands mediating adhesion of ie to the vascular endothelium. in the current study, the antigens exposed on the surface of ie with different isolates and various binding subpopulati...

mycobacterium tuberculosis (h37rv strain) was used in this study. the bacterial cells were disintegrated by sonication. the separation and characterization of the soluble molecules were attempted by various techniques including gel filtration, ion exchange chromatographies and polyacrylamide gel electrophoresis, using sds and 2me. eight protein molecules with molecular weights ranging from 6.3 ...

background: some antigens of h. pylori are excreted into the stool of infected people. these antigens can be used to detect the infection by immunoassays such as elisa. our aim was to identify these antigens by immunoblotting and affinity chromatography techniques.   methods: four different antigenic preparations, namely, whole cell sonicate (wcs), outer membrane proteins (omps), cytoplasmic an...

the basic pathogenic step in the process of tumor growth, invasion and metastasis is tumor-induced angiogenesis. the aim of this study was to evaluate the angiogenesis in colorectal carcinoma by microvascular density (mvd) determination with ihc (immunohistochemistry) method and to determine if and how angiogenesis correlates with clinicopathologic parameters. sixty two archival, paraffin embed...

background it is important to differentiate whether isolated anti-hbc is due to false positive results or the prior exposure to hepatitis b virus, because individuals with false-positive anti-hbc can benefit from vaccination and their blood can be safely transfused. to distinguish between these two conditions, we evaluated the serologic response to hepatitis b vaccine. methods ninety subjects w...

Background: Echinococcosis is a zoonotic parasitic disease caused by the larval stage of Echinococcus granulosus. Several native and recombinant antigens, derived from different stages of E. granulosus life cycle, have been used for vaccine trials. In vitro reared adult worms are good candidates for vaccination as they do not produce fertile egg/s and do not have any risk of contamination for r...

background: cancer/testis antigens (ctas) are members of a group of proteins which are normally expressed in testis germ cells and to a lesser extent in the ovaries. because of recent reports about their aberrant and specific expression in some tumoral tissues, they may play a role as new candidates for targeted therapy. therefore, the study of the expression pattern of these biomarkers and its...