introduction transfusion of red blood cells is a key component in the resuscitation of massively hemorrhaging patients post-injury. little is known about the functional status of patients at discharge or the outcome of patients after discharge from acute hospitalization. we assessed the changes among major trauma patients who had received massive transfusions. materials and methods this article...

In the Royal Maternity Hospital, Belfast, in common with other centres treating haemolytic disease of the newborn, the number of infants requiring exchange transfusion has been increasing steadily in the past few years. In 1950 there were seven live-born affected infants, of whom five were treated, all successfully, by exchange transfusion, in 1954 there were 42 live-born affected infants of wh...

During 23 exchange transfusions, the granulocytes from 27 donors and 16 newborn infants were tested for opsonic activity and granulocyte function by the nitrobluetetrazolium test. Granulocyte function in a newborn baby receiving an exchange transfusion can be altered positively or negatively, depending on the quality of the donor's blood. If exchange transfusion is used in the management of neo...

The first recorded case of recovery from hepatic coma after an exchange blood transfusion was that of Lee and Tink (1958). They gave two exchange transfusions of fresh blood to a boy aged 13 who was deeply jaundiced and comatose. After the first transfusion of 3,260 ml. his condition was unchanged, but when a second exchange of 3,140 ml. was given he improved and recovered completely. Trey et a...

Background Jaundice is one of the most common problems in neonatal period. Although the efficacy of exchange transfusion in the treatment of neonatal jaundice is knownand quickly reduces blood bilirubin levels, but severe neonatal hyperbilirubinemia is associated with significant morbidity and mortality. We conducted this study to investigate the risk factorsof severe hyperbilirubinemia in neon...

Blood pressure changes as a function of the rates of blood withdrawal and infusion were determined during exchange blood transfusion in 2 preterm newborn infants. 10 ml blood withdrawal and infusion completed within 3 minutes resulted in reversible changes in aortic pressure, whereas the same procedure completed within 45 to 60 seconds resulted in a progressive fall in the systolic pressure and...