نتایج جستجو برای: ethyl maltol

تعداد نتایج: 34589  

2016
C. Schmidt T. Ahmad Z. Tulassay D. C. Baumgart B. Bokemeyer S. Howaldt A. Stallmach C. Büning Daniel C. Baumgart Bernd Bokemeyer Carsten Büning Ulf Helwig Stefanie Howaldt Dietrich Hüppe Annette Krummenerl Thomas Krummenerl Tanja Kühbacher Wilfried Landry Andreas Lügering Christian Maaser Michael Mroß Ursula Seidler Andreas Stallmach Jürgen Stein Niels Teich Gabor Horvath Tünde Kristóf András László Tamás Molnár Ágnes Salamon Zsolt Tulassay Áron Vincze Pierre Krayenbuehl Tariq Ahmad Ian Beales Matthew Brookes Simon Campbell Fraser Cummings Ronald Ede David Elphick Alan Ireland Deepak Kejariwal Andy Li John Mansfield

BACKGROUND Ferric maltol was effective and well-tolerated in iron deficiency anaemia patients with inflammatory bowel disease during a 12-week placebo-controlled trial. AIM To perform a Phase 3 extension study evaluating long-term efficacy and safety with ferric maltol in inflammatory bowel disease patients in whom oral ferrous therapies had failed to correct iron deficiency anaemia. METHOD...

2015
Christoph Gasche Tariq Ahmad Zsolt Tulassay Daniel C. Baumgart Bernd Bokemeyer Carsten Büning Stefanie Howaldt Andreas Stallmach

BACKGROUND Iron deficiency anemia (IDA) is frequently seen in inflammatory bowel disease. Traditionally, oral iron supplementation is linked to extensive gastrointestinal side effects and possible disease exacerbation. This multicenter phase-3 study tested the efficacy and safety of ferric maltol, a complex of ferric (Fe) iron with maltol (3-hydroxy-2-methyl-4-pyrone), as a novel oral iron ther...

Journal: :Berichte der deutschen chemischen Gesellschaft 1894

2012
Mohsen Minaiyan Elahe Mostaghel Parvin Mahzouni

OBJECTIVES Iron chelators, such as maltol and kojic acid, have antioxidant and anti-inflammatory properties. They may have beneficial effects on inflammatory bowel disease (IBD) because iron can develop and aggravate inflammation in IBD. In the present study, the effect of selected iron chelators and anti-oxidants were evaluated on a model of trinitrobenzene sulfonic acid (TNBS)-induced colitis...

Journal: :Heart Rhythm 2023

Electronic nicotine delivery systems (ENDS) utilize “e-liquids” in order to generate “e-vapor”, an inhalable aerosolized mixture containing and flavors. Flavored ENDS are very popular among teens who vape, however, the possible cardiac electrophysiological harm of inhalation exposure flavored not fully understood. To test if flavoring carbonyls e-liquids compromises mitochondrial integrity, inc...

Journal: :Fermentation 2023

The primary processing method of coffee plays a crucial role in determining its flavor profile. In this study, roasted beans were subjected to three methods, i.e., natural (SC), washed (WC), and honey (MC), that analyzed by LC-MS/MS GC-MS metabolomics. Additionally, sensory evaluation was conducted the Specialty Coffee Association America (SCAA) assess characteristics. results showed 2642 non-v...

Journal: :Neuroscience letters 1998
Y Kashiwagi Y Nakamura Y Miyamae R Hashimoto M Takeda

Although chronic aluminum neurotoxicity has been well established, the mechanism of the toxicity has not been elucidated yet. In order to simplify the study of the aluminum neurotoxicity, we employed the pulse exposure of cultured rat cortical neurons to 250 microM aluminum-maltol for 1 h at the early stage (6 h after plating), which resulted in abnormal distribution of neurofilament L (NFL) an...

Journal: :Brazilian Journal of Development 2022

Brazil has a diversity of plant species and many them are medicinal plants used in the production herbal medicines. Passiflora incarnata is popularly known as passion fruit, its fruits aerial parts have anxiolytic sedative properties. Recent studies shown that P. several bioactive compounds such indole alkaloids, cyanogenic glycosides, maltol flavonoids. Among substances identified species, vit...

2017
Ouédraogo Noufou Hay Anne-Emmanuelle Ouédraogo Jean Claude W Sawadogo W Richard Tibiri André Lompo Marius Nikiema Jean-baptiste Koudou Jean Dijoux-Franca Marie-Genevieve Guissou Innocent Pierre

BACKGROUND Pterocarpus erinaceus Poir. belonging to Fabacae familly is used as medicinal plant in Burkina Faso's folk medicine. Roots of P. erinaceus are used to treat ulcer, stomach ache and inflammatory diseases. The objective of the present study was to carry out phytochemical composition of methanol (MeOH) and dichloromethane (DCM) extracts from Pterocarpus erinaceus roots, to isolate pure ...

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