to investigate uterine fluid and serum copper (cu) and zinc (zn) variations during the estrous cycle in water buffaloes, 71 genital tracts and blood samples were collected from the abattoir in urmia, iran. the phase of the estrous cycle was determined by examining ovarian structures; 18, 15, 16 and 22 were pro-estrous, estrous, met-estrous and diestrous, respectively. the uterine fluid was coll...

Sex hormonal milieus during the female fertility cycle modulate the tumor vascular permeability of breast cancer. It has been proposed that the liposomal formulated doxorubicin (ie, Doxil), given at the menstrual/estrous stage with the predicted highest tumor vascular permeability, allows significantly increased drug retention in the breast tumor. In the current study, syngeneic murine 4T1 mamm...

Introduction: In female rats sensitivity to antinociceptive treatment varies during estrous cycle stages. The role of GABA through GABAB receptor in nociception has been established. The aim of the present study is to investigate the effect of intercerebroventicular injection of GABAB receptor agonist (baclofen) and GABAB antagonist (CGP35348) on pain sensitivity during different stages of estr...

The response of dairy bulls to the urine of cows in various stages of the reproductive cycle was quantified by presenting 200 ml of urine in a stainless steel bowl to the stanchioned bulls for 10 min. Estrous mucus was also presented in the same manner. Sniffs, nose licks and flehmen responses were recorded. Of 15 bulls tested only 7, or 47%, met the criteria of two flehmens in response to estr...

The controls of food intake differ in male and female rats. Daily food intake is typically greater in male rats, relative to female rats, and a decrease in food intake, coincident with the estrous stage of the ovarian reproductive cycle, is well documented in female rats. This estrous-related decrease in food intake has been attributed to a transient increase in the female rat's sensitivity to ...

Five experiments were conducted to test the hypothesis that psychosocial stress interferes with the estrous cycle of sheep. In experiment 1, ewes were repeatedly isolated during the follicular phase. Timing, amplitude, and duration of the preovulatory luteinizing hormone (LH) surge were not affected. In experiment 2, follicular-phase ewes were subjected twice to a "layered stress" paradigm cons...

Method Twenty female Sprague Dawley rat (SD rat) were randomly divided into two groups according to their bedding types. The 1 group was raised in wood shaving bedding as a control and 2 one was in corncob bedding as an endocrine disrupting agent. Each group was checked daily for the first day of vaginal opening, and their vaginal smears were collected to determine estrous cyclicity after vagin...

Traumatic and stressful events during childhood are associated with the development of eating disorders. We conducted an animal study to test if association stress in childhood affects ingestive behavior later in life by using female rats that have an adjusted estrous cycle. First, electrical impedance of the vagina was conducted to test estrous cycle adjustment. Second, the effects of 6 h per ...

We evaluated the changes in estrous cycle of female rats fed either high carbohydrate or high protein diets for 42 days relatively to commercially available rodent pellets. Animals fed high carbohydrate diet showed a lengthened estrus cycle while those fed with a high protein diet could not continue a healthy estrous cycle. Animals received a protein rich diet showed a lengthened estrus cycle w...

Methomyl is an oxime carbamate pesticide that is widely used in the Philippines. This insecticide is known to be an endocrine disrupting chemical and a potent genotoxic in mammalian cells. However, limited studies were conducted specifically on its direct effects on estrous cycle and its teratogenic effect. This study aimed to (a) assess the effect of methomyl on the body weight and on the estr...