Estradiol valerate (Exogenous estrogen) is a synthetic ester and is also a female estrogen hormone. There arestudies showing that estradiol may have anticancer effects. This study was performed to reveal the effects ofexogenous estrogens on the viability of cervical cancer cells in cell culture. We used Hela cells as our cell linein this study. Hela cells were exposed to 0.0001, 0.001, 0.01, 0....

Hormones have been used to change phenotypic sex in many fish species. However, information specific changing brown trout Salmo trutta is lacking. This study compared the effectiveness of two different 17β-estradiol (estradiol) concentrations (20 mg/kg and 30 mg/kg) fed for 60 days, beginning at initial feeding. At 456 days post-initial feeding, 20 treatment groups were 84% 86% female, respecti...

Introduction: Beside its autonomic functions, the nucleus paragigantocellularis lateralis (LPGi) is involved in the descending pain modulation. 17β-Estradiol is a neuroactive steroid found in several brain areas such as LPGi. Intra-LPGi microinjection of 17β-estradiol can elicit the analgesic responses. 17β-Estradiol modulates nociception by binding to estrogenic receptors as wel...

results the mean ± sd of the clonic seizure threshold was 61.84 ± 8.53 in the group that received estradiol, while it was 71.70 ± 10.85 in the control group, 64.69 ± 3.23 in rats with laparotomy without removing the ovaries, 51.30 ± 6.84 in rats with laparotomy and removing the ovaries, 52.7 ± 7.18 in ovariectomized rats that received sesame oil as vehicle, and 59.2 ± 4.91, in the soy groups. t...

The aim of this study was to evidence the ability vegetable oil-based hybrid microparticles (HMP) be an efficient and safe drug delivery system after subcutaneous administration. HMP resulted from combination a thermostabilized emulsification process sol–gel chemistry. First all, castor oil successfully silylated by means (3-Isocyanatopropyl)trimethoxysilane in solvent-free catalyst-free condit...

results the results indicated that ghrelin significantly decreased thyroid hormone concentrations, whereas estradiol increased these concentrations. the simultaneous injection of ghrelin and estradiol significantly decreased the inhibitory effect of ghrelin on thyroid hormone concentrations (p < 0.05). conclusions according to the results of this study, both ghrelin and estradiol affect the con...

conclusions this study revealed that lod in females with pcos with a serum e2 > 40 pg/ml was sufficient and safe to trigger development of ovarian follicles followed by clinical pregnancy. results there was significant difference in the average starting time of ovulation and continuing spontaneous ovulation of cases with pcos with e2 levels > 40 pg/ml, compared with ones with e2 ≤ 40 pg/ml (p =...

The present study was carried out with the objective of evaluating, in castrated rats, utero trophic, hormonal and biochemical activities aqueous extracts Buchholzia coriacea (BC) Cogniauxia podolaena (CP) leaves. Each extract administered at dose 600 mg/Kg rats did not cause a significant change fresh weight/dry weight ratio uterus compared to given distilled water. However, those receiving 17...