Human immunodeficiency virus type 1 (HIV-1) can be transmitted through breast-feeding and through contaminated blood donations. Copper has potent biocidal properties and has been found to inactivate HIV-1 infectivity. The objective of this study was to determine the capacity of copper-based filters to inactivate HIV-1 in culture media. Medium spiked with high titers of HIV-1 was exposed to copp...

Metallic copper alloys have recently attracted attention as a new antimicrobial weapon for areas where surface hygiene is paramount. Currently it is not understood on a molecular level how metallic copper kills microbes, but previous studies have demonstrated that a wide variety of bacteria, including Escherichia coli, Staphylococcus aureus, and Clostridium difficile, are inactivated within min...

HD (Huntington's disease) is caused by a polyQ (polyglutamine) expansion in the huntingtin protein, which leads to protein misfolding and aggregation of this protein. Abnormal copper accumulation in the HD brain was first reported more than 15 years ago. Recent findings show that copper-regulatory genes are induced during HD and copper binds to an N-terminal fragment of huntingtin, supporting t...

plant growth is often limited by low levels of soil micronutrients such as copper (cu), ‎especially in calcareous salt-affected soils of arid and semiarid regions. the aim of this ‎work was to investigate individual and combined effects of salinity and cu on growth, leaf ‎relative water content (lrwc), cell membrane permeability, lipid peroxidation, and total ‎phenolic content (tpc) of rosemary...

This study was performed in order to determine the relative and combined effects of ethanol, a low protein diet and steroid treatment on bone, muscle, liver, and urinary and faecal excretion of zinc, copper and iron in 64 rats divided into eight groups treated following the Lieber-DeCarli liquid diet technique, with and without dexamethasone, 1 mg/l. Steroids showed a lack of effect on liver zi...

Copper metallochaperones supply copper to cupro-proteins through copper-mediated protein-protein-interactions and it has been hypothesized that metallochaperones thereby inhibit copper from causing damage en route. Evidence is presented in support of this latter role for cyanobacterial metallochaperone, Atx1. In cyanobacteria Atx1 contributes towards the supply of copper to plastocyanin inside ...

Copper wires have been attracting much attention for Large Scale Integration (LSI) bonding because of their excellent mechanical and electrical properties, in addition to their low material cost. The ends of these wires are usually joined to pads or through-holes on a printed circuit board, and lead-free soldering is one of the popular bonding methods. Since the deformation resistance of solder...

Trace metals, especially copper, are commonly occurring contaminants in harbors and marinas. One source of copper to these environs is copper-based antifouling coatings used on vessel hulls. The objective of this study was to measure dissolved copper contributions from recreational vessel antifouling coatings for both passive leaching and hull cleaning activities. To accomplish this goal, three...

Diabetic individuals frequently suffer from skin pathologies, especially in their feet. Co-existing peripheral vascular disease and neuropathy exacerbate the capacity of these individuals to cope with infections, minor cuts and wounds, often leading to hard to treat and chronic ulcers. Copper has potent anti-fungal and antibacterial properties. Copper is also an essential trace element vital fo...

SUMMARY The purpose of this study is to compare the level of zinc, copper and the ratio of zinc to copper in serum of patients who are suffering from acute myocardial infarction with healthy men. In 10 ml blood samples from 45 men on the second day of myocardial infarction and 51 healthy men volunteers matched for age, serum zinc, copper, cholesterol and triglycerides were measured. Zinc and c...