Red blood cells (RBCs) -- erythrocytes suspended in plasma tend to aggregate and form rouleaux. During aggregation the first stage consists formation of RBC doublets [Blood cells, molecules, diseases 25, 339 (1999)]. While aggregates are normally dissociated by moderate flow stresses, under some pathological conditions becomes irreversible, which leads high viscosity vessel occlusion. We perfor...

background: evidence is accumulating that venous thromboembolism is not limited to coagulation system and immune system seems to be involved in formation and resolution of thrombus. some studies have demonstrated the role of inflammatory factors in deep venous thrombosis (dvt) of limbs; however, there has not been such study in the patients with cerebral venous sinus thrombosis (cvst). the purp...

Objective: Ionizing radiation produces free radicals which induce DNA damage and cell death. Origanum vulgare leaf extract (OVLE) is a natural compound and its capability of scavenging free radicals and its antioxidant activity have been demonstrated by many researchers. In this study, using micronucleus assay, radioprotective effect of OVLE against clastogenic and cytotoxic effect of gamma irr...

Background: There is unprecedented increase in the processing and packaging of many plant materials into food supplements, herbal medicine, skincare and cosmetic products for human needs. Baphia nitida is used for topical skincare products. Toluene, a toxic aromatic solvent, is increasingly being used in the production of these skincare and cosmetic products in many industries. This study ass...

In this study morphological characterization of leukocyte and erythrocyte were investigated in central Asian tortoise (Testudo horsfieldii) in Iran. 7 males and 7 females were used in this study. Erythrocyte and leukocyte morphology were described using Wright´s technique. The sizes of erythrocyte and their nuclei were measured using an ocular micrometer under objective lenses (100x). Resul...

background: psoriasis is a chronic and inflammatory dermatologic disease. inflammatory biomarkers such as c-reactive protein (crp) and erythrocyte sedimentation rate (esr) are known as immediate and delayed inflammatory biomarkers, respectively. due to the fact that anti-inflammatory drugs such as infliximab are widely used in psoriasis treatment, the aim of this study was to evaluate esr, crp ...

background cellular level of enzyme activity can serve as a reliable biomarker in the event of environmental/chemical insults. objectives the present study investigated time-dependent alterations of erythrocyte glutathione s-transferase (ery-gst) activity of non-malarious guinea pigs (cavia tschudii) administered with pyrimethamine/sulfadoxine and artemether/lumefantrine combination therapies. ...

Background: Blood is permanently exposed to oxidation stress and therefore has a high antioxidants capacity. Many different factors increasing the demand for the antioxidant capacity can be observed in the stored blood of donors. Consequently, damage to erythrocytes by free radicals may occur. So it is useful to control the alternation of anti-oxidant enzymes in stored blood at different days o...