BACKGROUND Traditional Chinese medicine (TCM) herbal formulae provide valuable therapeutic strategies. However, the active ingredients and mechanisms of action remain unclear for most of these formulae. Therefore, the identification of complex mechanisms is a major challenge in TCM research. METHODS This study used a network pharmacology approach to clarify the anti-inflammatory and cough sup...

The aim of the study is to illuminate possibilities using hawthorn (Crataegus spp) as rootstock in loquat (Eriobotrya japonica Lindl.) growing. For this aim, cv. Hafif Çukurgöbek (HÇG) was budded on rootstocks 8th February, 18th May, 7th August, and 31st October 2019 with chip budding method field conditions. percent bud-take successes were recorded after 45 days operations. In bud-take, top cu...

One of causes in decreasing quantity and quality spermatozoon is disease. Increased blood glucose levels can trigger demage spermatogenesis the testes, thereby reducing spermatozoa production. Biwa leaves (Eriobotrya japonica (Thunb.) Lindl.) contain triterpenes which are expected to overcome cauda epididymis. To investigate this problem, an experimental test nano herbal biwa was carried out a ...

Objectives: Eriobotrya japonica belongs to the Rosaceae. Studies have shown that the flowers of this plant are rich in phenolic and flavonoid compounds. Accorrdingly, the evaluation of antioxidative effects of Eriobotrya japonica Flower Extract (EJFE) have been performed in vitro. Material and Methods: In this study, to investigate the influences of components of EJFE on its antioxidative activ...

Mimetics of the second mitochondria-derived activator of caspases (Smac) increase the sensitivity of tumor cells towards chemotherapeutics in cancer therapy [1]. Our aim was the discovery of naturally derived small molecule Smac-mimetics from the medicinal plant Eriobotrya japonica Lindl. (Rosaceae), which is known to contain cytotoxic constituents [2]. Using a previously generated and validate...