In order to elucidate a part of calmodulin actions in the hyperproliferative state in human epidermis, calmodulin activities in the psoriatic and in the normal human epidermis were determined using calmodulin-deficient phosphodiesterase from bovine heart and purified pig skin epidermal calmodulin as a standard. Skin samples were obtained from 11 normal healthy controls and from both the uninvol...

CONTEXT Recent progress in the field of epithelial culture techniques has allowed the development of culture systems in which the reconstructed epidermis presents characteristics of morphological differentiation similar to those seen in vivo. Human epidermis reconstructed in vitro may be used as the best alternative for the in vitro testing of the toxicology and efficiency of products for topic...

The dermal side of the chick embryonic skin was observed by scanning electron microscopy (SEM) after the removal of dermal components. Epidermis free of dermis was prepared as follows: Tissues were fixed, hydrolyzed with hydrochloric acid (HC1), digested with collagenase or trypsin, and processed for SEM observation. The epidermis from the anterior tarsometatarsus and the foot pad was examined....

The lipide composition of epidermis and dermis under the influence of the hair growth cycle and following the topical application of methylcholanthrene was inves tigated. The percentage of cholesterol and phospholipide was lowest in anagen and telogen epidermis, was nearly doubled in early and late hyperplastic epidermis, and rose to even higher values in squamous-cell carcinomas. The cholester...

Water stress effects on winter and spring leaves anatomy were investigated in experiments conducted at the experimental field of SB University of Kerman using five wheat cultivars.Xylem and phloem elements diameter and mesophyll, bundle sheath and epidermal cells area were measured in transverse sections prepared from middle parts of the leaves. Results showed that significant difference exists...

Background: The radiation emitted from electromagnetic fields (EMF) can cause biological effects on prokaryotic and eukaryotic cells, including non-thermal effects. Objective: The present study evaluated the non-thermal effects of wireless fidelity (Wi-Fi) operating at 2.4 GHz part of non-ionizing EMF on different pathogenic bacterial strains (Escherichia coli 0157H7, Staphylococcus aureu...

This study demonstrates the effectiveness of a peptide shuttle in delivering diclofenac into and through human epidermis. Diclofenac was conjugated to a novel phenylalanyl-N-methyl-naphthalenylalanine-derived diketopiperazine (DKP) shuttle and to TAT (a classical cell penetrating peptide), and topically applied to human epidermis in vitro. DKP and TAT effectively permeated into and through huma...

a 3-month-old short haired pointer with crusty local alopecia around the eyes was presented to smallanimal hospital of tehran university. scraping and biopsy were obtained from lesions of affected area.notoedres sp. was diagnosed in skin scraping by parasitologic examination. furthermore, histopathology oflesions demonstrated moderate hyperplastic epidermis, parakeratosis and acanthosis.