We have compared the haemodynamic effects of ephedrine alone with ephedrine and colloid for the treatment of hypotension produced by subarachnoid anaesthesia in 30 patients aged 60-90 yr with fractures of the neck of femur. Group one received ephedrine as an initial bolus dose of 0.2 mg kg-1 followed by an infusion of 0.5 mg kg-1 h-1. Group two received ephedrine and colloid (polygeline, Haemac...

INTRODUCTION Propofol and Ephedrine are commonly used during anesthesia maintenance, the former as a hypnotic agent and the later as a vasopressor. The addition of propofol to ephedrine or administration of ephedrine before propofol injection is useful for decreasing or preventing propofol related hemodynamic changes and vascular pain. This in vitro study evaluated the antibacterial effect on c...

OBJECTIVE To investigate dose-related effects of ephedrine on olfactory function in healthy subjects. DESIGN Placebo-controlled, randomized, double-blind study. METHODS Drug effects were assessed using olfactory and trigeminal psychophysical measures (intensity ratings, odor discrimination, butanol and formic acid thresholds); nasal patency was assessed by means of anterior rhinoresistometr...

the effect of ephedrine at 0 (e0c0, n = 10), 8 (e8c0, n = 10) and 10 (e10c0, n = 10) mg per kg metabolic body weight or mixture of ephedrine/caffeine, at doses of 8 mg ephedrine/80 mg caffeine (e8c80, n = 10), or 10 mg ephedrine/100 mg caffeine (e10c100, n = 7), per kg metabolic body weight on body composition of feedlot mehraban ram lambs (8-month-old) was studied. the lambs were fed for 95 da...

The effect of ephedrine at 0 (E0C0, n = 10), 8 (E8C0, n = 10) and 10 (E10C0, n = 10) mg per kg metabolic body weight or mixture of ephedrine/caffeine, at doses of 8 mg ephedrine/80 mg caffeine (E8C80, n = 10), or 10 mg ephedrine/100 mg caffeine (E10C100, n = 7), per kg metabolic body weight on body composition of feedlot Mehraban ram lambs (8-month-old) was studied. The lambs were fed for 95 da...

Spinal anaesthesia for Caesarean section is associated with an unacceptably high incidence of hypotension despite the administration of an intravenous fluid preload and the use of uterine displacement. The theoretical benefits of preventing hypotension as opposed to treating it as it occurs are the avoidance o f considerable maternal discomfort, a reduced risk o f serious cardiovascular or resp...

BACKGROUND Phenylephrine and ephedrine are both used to maintain arterial blood pressure during spinal anesthesia for cesarean delivery. Usually, either drug is given alone but several previous studies have described combining the drugs. However, the effect of varying the proportion of vasopressors in such combinations has not been reported. METHODS One-hundred-twenty-five parturients having ...

Human consumption of ephedrine and caffeine in dietary supplements has been associated with a number of adverse effects including changes in the ECG, myocardial infarction, hyperthermia, and, in rare instances, death. The purpose of this study was to investigate the potential mechanisms associated with the cardiotoxicity of combined ephedrine and caffeine ingestion. Seven- and fourteen-week-old...

The purpose of this study is to assess the effects of ephedrine on onset time of rocuronium, by comparing onset time when using rocuronium alone and with priming with rocuronium. In this randomized clinical trial, 120 patients with the American Anesthesiologists Society (ASA) class I/II who required laryngoscopy and tracheal intubation for elective surgery were assigned to 4 groups. Priming dos...

PURPOSE To compare maternal and fetal effects of intravenous phenylephrine and ephedrine administration during spinal anesthesia for cesarean delivery in high-risk pregnancies. SOURCE An extensive literature search was conducted using the US National Library of Medicine, MEDLINE search engine, Cochrane review, and Google Scholar using search terms "ephedrine and phenylephrine," "preterm and t...