Background: Endometrial stroma sarcoma (ESS) is usually formed of neoplastic cells similar to proliferative endometrial cells and comprises less than 10% of all uterine sarcomas. Presence of concurrent sex cord element with these tumors is rare. Materials and Methods: A 36 year-old woman,from yazd complaining of abnormal vaginal bleeding and history of G4P3Ab1Ch3 referred. On both occasions aft...

PURPOSE To evaluate the clinical and epidemiological risk factors for endometrial cancer in postmenopausal women with endometrial polyps, as well as the genetic polymorphism of the progesterone receptor (PROGINS). METHODS A case-control study was designed with 160 postmenopausal women with endometrial polyps, compared to a normal Control Group of 400 postmenopausal women. The genotyping of PR...

INTRODUCTION Hysteroscopy is considered the 'gold standard' procedure in assessing uterine pathology however it is more expensive and invasive method than ultrasonography. An alternative to the diagnostic hysteroscopy is sonohysterography. AIM To evaluate the usefulness of sonohysterography in detecting endometrial polyps in female patients diagnosed with infertility. MATERIAL AND METHODS W...

OBJECTIVE To estimate the incidence of recurrent postmenopausal bleeding among women who were diagnosed with an endometrial thickness greater than 4 mm. METHODS We designed a prospective cohort study and included consecutive women not using hormone replacement therapy, presenting with a first episode of postmenopausal bleeding. We evaluated patients who had an endometrial thickness greater th...

A 64-yr-old postmenopausal woman with high-grade squamous intraepithelial lesion and atypical glandular cell of undetermined significance on her Pap test was found to have endometrial serous carcinoma (high grade) involving a polyp in a subsequent endometrial biopsy. She underwent hysterectomy and bilateral salpingo-oophorectomy with multiple biopsies of the peritoneum. Microscopic examination ...

Endometrial polyps are one of the most common etiologies of abnormal genital bleeding in both premenopausal and postmenopausal women. They are hyperplastic overgrowths of endometrial glands and stroma that form a projection from the surface of the endometrium. They may also be asymptomatic. The great majority of endometrial polyps are benign, but malignancy occurs in some women. Single or multi...

Tamoxifen is utilized as adjuvant therapy in women diagnosed with breast cancer. In these patients, despite its positive risk/benefit ratio, tamoxifen may cause secondary effects on the endometrium, with increased risk of malignant diseases. So, the first question to be answered is: “Does tamoxifen increase the incidence of endometrial abnormalities?” The literature presents two meta-analysis-s...

Endometrial stromal tumors are rare, and endometrial stromal nodule is the least common. In the region of Middle Jutland, Denmark, only two cases are reported since 1995. The nodules are benign; nevertheless, hysterectomy is the treatment of choice. Tumor margins are required for diagnosis and essential to differentiate it from an invasive stromal sarcoma whose prognosis is very different. We r...