The variants of angiotensin converting enzyme (ACE) and matrix metalloproteinases (MMPs) genes might be involved in the pathogenesis of end stage renal disease (ESRD) and hypertension. We studied the ACE insertion/deletion (I/D) and MMP-7 A-181G variants in 99 unrelated ESRD patients and 117 individuals without renal complications from Western Iran with Kurdish ethnic background. The frequency ...

One-hundred and sixteen children with ESRD were registered in Shiraz Pediatric Hemodialysis Center in Nemazee Hospital, a referral center in the south of Iran, from 1990 to 1999. Very small children are not dialysed in this center due to technical problems. The age range of children in this center was 2-16 years, mean age was 10.4±3.6 years and male to female ratio was 1.4. Major causes of ...

OBJECTIVE To review the contribution of vesicoureteral reflux and reflux nephropathy to end-stage renal disease. DATA SOURCE Published research articles and publicly available registries. RESULTS Vesicoureteral reflux (VUR) is commonly identified in pediatric patients and can be associated with reflux nephropathy (RN), chronic kidney disease (CKD), and rarely end-stage renal disease (ESRD)....

chronic kidney disease is one of the most common complication of systemic lupus erythematosus, which if untreated can lead to  the end-stage renal disease (esrd). early diagnosis and adequate treatment of lupus nephritis (ln) is critical to prevent the chronic kidney disease incidence and to reduce the development of esrd. the treatment of ln has changed significantly over the past decade. in p...

kaposi᾽s sarcoma (ks) can develop in 0.06% to 4.1% of kidney transplant recipients. here we describe a case of 50-year-old man who developed ks a few months after kidney transplantation . after transplantation, he had delayed graft function and was managed by anti-thymocyte globulin (atg) for five days. at the discharge, his immunosuppressive therapy was prednisolone 20 mg/day, ttacrolimus (ppr...

background and aims: mental disorders may negatively affect on the quality of life in hemodialysis patients and their response to treatment. the aim of present study was to examine the prevalence of depression and related risk factors in hemodialysis patients. methods: in this cross-sectional study, during june 2013 to september 2013, 217 patients with hemodialysis whom were admitted to kerman ...