– On the morning of September 18, 1989, a category-four hurricane struck eastern Puerto Rico with a sustained wind speed in excess of 46 m/sec. The 24-h rainfall accumulation from the hurricane ranged from 100 to 339 mm. Average rainfall intensities ranging from 34 to 39 mm/h were calculated for 4 and 6 h periods, respectively, at a rain gage equipped with satellite telemetry, and at an observe...

In the neocortex, inhibitory interneurons of the same subtype are electrically coupled with each other via dendritic gap junctions (GJs). The impact of multiple GJs on the biophysical properties of interneurons and thus on their input processing is unclear. The present experimentally based theoretical study examined GJs in L2/3 large basket cells (L2/3 LBCs) with 3 goals in mind: (1) To evaluat...

In this chapter, a new technology for low‐temperature (LT, 400°C) boron deposition is developed, which provides a smooth, uniform, closed LT boron layer. This technolo‐ gy is successfully employed to create near‐ideal LT PureB (pure boron) diodes with low, deep junction‐like saturation currents, allowing full integration of LT PureB photodio‐ des with electronic interface circuits and other sen...

The optimal treatment (liver transplantation [LT] vs surgical resection [SR]) for early-stage hepatocellular carcinoma (HCC) remains controversial.A total of 209 SR patients and 129 LT patients were identified at our institution. After eliminating 27 patients with Child-Pugh C, the data from 209 SR patients and 102 LT patients were analyzed using a propensity score matching (PSM) model. Forty-s...

The current paper is focussed on the nodular cast iron ASTM 80-55-06 (EN-GJS-600). The individual microstructure was investigated by light and scanning electron microscopy as well as micro-hardness measurements. Stress-controlled fatigue tests were performed at ambient temperature with testing frequencies of f = 5 Hz and f = 150 Hz. The cyclic deformation behaviour was characterised by means of...

Dysfunction of gap junctions (GJs) caused by mutations in connexin26 (Cx26) and Cx30 accounts for nearly half of all cases of hereditary nonsyndromic deafness cases. Although it is widely held that GJs connecting supporting cells in the organ of Corti mainly provide ionic pathways for rapid removal of K+ around the base of hair cells, the function of GJs in the cochlea remains unknown. Here we ...

Spontaneous activity in the central nervous system is strongly suppressed by blockers of gap junctions (GJs), suggesting that GJs contribute to network activity. However, the lack of selective GJ blockers prohibits the determination of their site of action, i.e. neuronal versus glial. Astrocytes are strongly coupled through GJs and have recently been shown to modulate synaptic transmission, yet...

Murine macrophages have been classified as either susceptible or nonsusceptible to killing by anthrax lethal toxin (LT) depending upon genetic background. While considered resistant to LT killing, we found that bone marrow-derived macrophages (BMMs) from DBA/2, AKR, and C57BL/6 mice were slowly killed by apoptosis following LT exposure. LT killing was not restricted to in vitro assays, as splen...

Estamos realizando mediciones en el laboratorio de las ĺıneas de emisión de iones importantes en la astrof́ısica, en el rango espectral de rayos-X de entre 1 y 400 Å , que cubrirán las misiones espaciales Chandra, XMM, Astro-E y EUVE. Los datos, obtenidos en un ambiente controlado a densidades similares a las de coronas estelares, son usados para verificar la exactitud y completez de códigos de ...

Electrical synapses are a type of cellular membrane junction referred to as gap junctions (GJs). They provide a direct way to exchange ions between coupled cells and have been proposed as a structural basis for fast transmission of electrical potentials between neurons in the brain. For this reason GJs have been regarded as an important component within the neuronal networks that underlie synch...