and Emdogain® to Plastic by Enzyme-linked Immunosorbent Assays (ELISA) To assess whether recombinant amelogenin and Emdogain® used in the cell attachment experiments indeed coupled to plate surfaces, we coated a two-fold serial concentration range (1.5 g–1.5 and 0 ng/well) of each protein in duplicate on Dyclone 2HB 96-microwell plates overnight at 4°C in MAM, imitating the conditions used in t...

Root denudation following gingival recessions promotes carious or non-carious cervical lesions with hypersensitivity and esthetic discomfort. To satisfy the immediate demand of the patients, general practitioners used to perform restorative procedures including cervical fillings or bonding techniques (resin-modified restorative glass ionomer, microfin resin composite) to cover the lesion. This ...

Twenty-seven patients were randomized into two treatment groups following single tooth extraction in the incisor, canine and premolar area. In the test group, the alveolar socket was grafted with Straumann Bone Ceramic (SBC), while in the control group, Bio-Oss deproteinized bovine bone mineral (DBBM) was applied. In both groups, a collagen barrier was used to cover the grafting material. Compl...

BACKGROUND AND OBJECTIVE Emdogain (EMD), consisting mostly of amelogenin, is used in periodontal therapy to regenerate lost connective tissue. Emdogain is applied onto periodontally affected root surfaces, where it becomes exposed to proteolytic enzymes. In this study, we aimed to find out whether gingival crevicular fluid or matrix metalloproteinases (MMPs) could degrade EMD, and whether this ...

Periodontal hastalıklar sonucunda ortaya çıkan defektleri iyileştirmek amacıyla konan çözümlerin yeterli olmaması sebebiyle; araştırmalar defekt bölgelerine uygulanabilecek yeni ajanlar geliştirmeye yönelmiştir. En umut verici çalışmaların Emdogain ve mineralizan peptitler kullanılarak yapıldığı görülmüştür. Bu derleme peptitlerin periodontal defektlere uygulanması ile oluşan sonuçları hangi bö...

Objective: The aim of this study is to evaluate the histological and clinical outcomes intrabony defects treatment using regenerative periodontal therapy with enamel matrix proteins (Emdogain, EMD). Material And Method:Ten patients chronic periodontitis were included in randomized, controlled study. Two groups received conservative therapy. In test group, different teeth EMD. control group only...

OBJECTIVE The aim of the present study was to evaluate by clinical means the effect of enamel matrix proteins on the healing of a soft tissue wound produced by periodontal pocket instrumentation. MATERIAL AND METHODS The study was performed as an intra-individual, longitudinal trial of 3 weeks duration with a double-masked, split-mouth, placebo-controlled and randomized design. The patient ma...

objective: the aim of this study was to compare subepithelial connective tissue grafts (sctg) and coronally advanced flaps (caf) with the addition of emdogain in the treatment of gingival recession. materials and methods : this interventional randomized controlled clinical trial involved eleven patients and 31 teeth demonstrating facial recessions of > 2 mm identified as miller's class i or ii....