Previous investigators have suggested that the DTL fibre electrode might not be suitable for the recording of replicable electroretinograms. We present experimental evidence that when used adequately, this electrode does permit the recording of highly reproducible retinal potentials.

Twenty-two of 23 obligate female carriers in nine families with known X-chromosome-linked retinitis pigmentosa were detected on the basis of abnormal full-field electroretinograms (ERGs). Only 14 of these carriers had fundus findings characteristic of the carrier state. Electroretinograms of carriers were either reduced in amplitude to white light under dark-adapted conditions or delayed in con...

OBJECTIVE To describe retinal changes in acute zonal occult outer retinopathy (AZOOR). METHODS We investigated retinal function and morphologic changes in 5 patients (mean age, 33.6 years) with AZOOR and acute visual field loss in 1 or more zones using Stratus optical coherence tomography, multifocal electroretinograms, full-field electroretinograms, and Goldmann perimetry. RESULTS Goldmann...

PURPOSE To identify an animal model for the abnormal scotopic electroretinogram found in a majority of Duchenne and Becker muscular dystrophy patients. METHODS Ganzfeld electroretinograms were recorded in dark-adapted normal C57BL/6 mice, and two strains of mice with different X-linked muscular dystrophy mutations (mdx and mdxCv3). Responses for the right eye were averaged and the amplitudes ...

The pattern electroretinogram has been found to be abnormal in all except three cases of maculopathy. This is in contrast to other electrophysiological tests, which are frequently unaffected. The degree of reduction is related to the loss of visual acuity. The response to focal flashes is less affected than the response to pattern.