We present here a novel conjugated aptamer-gold nanoparticle (Apt-AuNPs) fluorescent probe and its application for specific detection of recombinant human erythropoietin-α (rHuEPO-α). In this nanobiosensor, 12 nm AuNPs function as both a nano-scaffold and a nano-quencher (fluorescent energy acceptor), on the surface of which the complementary sequences are linked (as cODN-AuNPs) and pre-hybridi...

Developing a nanobiosensor for non-invasive visualization of the AKT signaling pathways Amnon Bar-Shir, Nikita Oskolkov, Galit Pelled, Jeff W.M. Bulte, Michael T McMahon, and Assaf A. Gilad Radiology, Johns Hopkins University, Baltimore, MD, United States, Institute for Cell Engineering, Johns Hopkins University, Baltimore, MD, United States, F.M. Kirby Research Center, Kennedy Krieger Institut...

Nanotechnology is the manipulation of material on an atomic and molecular scale; by changing its physical, chemical and biological properties to produce novel materials, devices, and systems. Nanomaterials exhibit remarkable characteristics such as high surface to volume ratio, catalytic activity, and biocompatibility which make them suitable for various biomedical applications. Nanotechnology ...

Cortisol plays an important part in physiological procedures. Observing cortisol concentration as a stress indicator demonstrates the mode for diagnosis goal. The mechanism of presented nano biosensor is LSPR and performed based on nucleic acid aptamer functionalized with gold nanoparticles which have specific interaction cortisol. particular measurement was accomplished over from 0.05 -0.2 μg·...

Nanosensors can be defined as sensors based on nanotechnology. The aim of some nanobiosensor projects at potentially high volume applications in the public health sector, as preventing food poisoning where markets might be significant, while the other aim to improve on existing clinical practises by allowing the more quantification and rapid detection of bacteria and viruses. It should increase...

Early, rapid and ultrasensitive diagnosis of COVID-19 to facilitate high-throughput analysis without a high degree technical expertise or sophisticated equipment is necessary expand testing capability. Leveraging interdisciplinary proficiency in analytical chemistry, biomedical instrumentation, molecular biology, microfluidics, nanotechnology, considerable advances have been made develop novel ...