A novel ferrocene-based substrate for the ratiometric electrochemical detection of β-galactosidase was designed and synthesised. It was demonstrated to be an excellent electrochemical substrate for β-Gal detection with sensitivity as low as 0.1 U mL-1.

A novel amplification strategy based on DNAzyme functionalized gold nanoparticles was employed to enhance the sensitivity of an electrochemical sensor for detection of Pb2+. The detection limit is 0.028 nM, which is much lower than for other electrochemical DNAzyme sensors.

Determination of inorganic phosphate is of very high importance in environmental and health care applications. Hence knowledge of suitable analytical techniques available for phosphate sensing for different applications becomes essential. Electrochemical methods for determining inorganic phosphate have several advantages over other common techniques, including detection selectivity, stability a...

A novel electrochemical immunosensing strategy for the detection of sulfonamide antibiotics in milk based on magnetic beads is presented. Among the different strategies for immobilizing the class-specific anti-sulfonamide antibody to the magnetic beads--such as those based on the use of Protein A or carboxylate modified magnetic beads - ,the best strategy was found to be the covalent bonding on...

In this work, we fabricated an electrochemical sensor based on trimethyloctadecylammonium bromide and multi-walled carbon nanotubes-Fe3O4 hybrid (TOAB/MWCNTs-Fe3O4) for sensitive detection of tetrabromobisphenol A (TBBPA). The nanocomposite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM) and Fourier transform infrared spectroscopy (FT-IR) techniques. The ele...

We report a self-contained electrochemical enzyme linked immunosorbent assay in microchannel devices constructed from low temperature co-fired ceramic with screen-printed gold for fast and sensitive assays. No one has previously reported a device constructed from these materials for combined immobilization and electrochemical detection. These low temperature co-fired ceramic microchannel device...

The important biological roles of nitric oxide (NO) have prompted the development of analytical techniques capable of sensitive and selective detection of NO. Electrochemical sensing, more than any other NO detection method, embodies the parameters necessary for quantifying NO in challenging physiological environments such as blood and the brain. In this tutorial review, we provide a broad over...

a new signal amplification strategy based on simultaneous application of gold nanoparticles (aunps) and horseradish peroxidase (hrp) was employed to improve the sensitivity of an electrochemical immunoassay for detection of human igg (higg), as a model antigenic protein. this immunoassay system was fabricated on magnetic carboxyl-functionalized multi-walled carbon nanotubes (cooh-mwcnt/fe3o4 na...