The GuLF STUDY is a cohort study investigating the health of workers who responded to the Deepwater Horizon oil spill in the Gulf of Mexico in 2010. The objective of this effort was to develop an ordinal job-exposure matrix (JEM) of airborne total hydrocarbons (THC), dispersants, and particulates to estimate study participants' exposures. Information was collected on participants' spill-related...

In many applications, information is best represented as graphs. In a dynamic world, information changes and so the graphs representing the information evolve with time. We propose that historical graph-structured data be maintained for analytical processing. We call a historical evolving graph sequence an EGS. We observe that in many applications, graphs of an EGS are large and numerous, and t...

In 2007, we applied MCMC to approximately calculate the ratio of essential graphs (EGs) to directed acyclic graphs (DAGs) for up to 20 nodes. In the present paper, we extend our previous work from 20 to 31 nodes. We also extend our previous work by computing the approximate ratio of connected EGs to connected DAGs, of connected EGs to EGs, and of connected DAGs to DAGs. Furthermore, we prove th...

Background Engineered or enhanced geothermal systems (EGS) have been promoted as a technology that exploits geothermal heat and power production from regions of the crust devoid of shallow high enthalpy reservoirs (also referred to as high-grade hydrothermal resources) (e.g., MIT 2006). The status of EGS development was reviewed by Breede et al. (2013) who reported on 14 EGS projects that were ...

Phenylpropenes, a large group of plant volatile compounds that serve in multiple roles in defense and pollinator attraction, contain a propenyl side chain. Eugenol synthase (EGS) catalyzes the reductive displacement of acetate from the propenyl side chain of the substrate coniferyl acetate to produce the allyl-phenylpropene eugenol. We report here the structure determination of EGS from basil (...

EGS (external guide sequence) technology is a promising approach to designing new antibiotics. EGSs are short antisense oligoribonucleotides that induce RNase P-mediated cleavage of a target RNA by forming a precursor tRNA-like complex. The ftsZ mRNA secondary structure was modeled and EGSs complementary to two regions with high probability of being suitable targets were designed. In vitro reac...

RNase P, a ribonucleoprotein responsible for the 5' maturation of precursor tRNAs (ptRNAs) in all organisms, can be enticed to cleave any target mRNA that forms a ptRNA-like structure and sequence-specific complex when bound to an RNA, termed the EGS (external guide sequence). In the present study, F3H (flavanone 3-hydroxylase), a key enzyme in the flavonoid biosynthetic pathway that participat...

BACKGROUND Endoscopic transpapillary pernasal gallbladder drainage and endoscopic gallbladder stenting (EGS) have recently been reported to be useful in patients with acute cholecystitis for whom a percutaneous approach is contraindicated. The aim of this study was to evaluate the efficacy of permanent EGS for management of acute cholecystitis in elderly patients who were poor surgical candidat...

BACKGROUND The staged laparotomy in the operative management of emergency general surgery (EGS) patients is an extension of trauma surgeons operating on this population. Indications for its application, however, are not well defined, and are currently based on the lethal triad used in physiologically-decompensated trauma patients. This study sought to determine the acute indications for the sta...

REASONS FOR PERFORMING STUDY We hypothesised that the apparent geographical distribution of equine grass sickness (EGS) is partly attributable to suboptimal levels of soil macro- and trace elements in fields where EGS occurs. If proven, altering levels of particular elements could be used to reduce the risk of EGS. OBJECTIVES To determine whether the geographical distribution of EGS cases in ...