نتایج جستجو برای: efflux genes
تعداد نتایج: 443427 فیلتر نتایج به سال:
conclusions high-level antibiotic resistance can occur as a result of multidrug efflux pumps combined with other mechanisms of resistance. however, the association between over-expression of these genes and highly resistant clinical isolates cannot be ignored. results our results confirmed 203 and 60 p. aeruginosa isolates from burn and non-burn specimens, respectively. the most antibiotic resi...
Background and Aims: Pseudomonas aeruginosa is one of the most important pathogens of nosocomial infections, especially in the ICU (Intensive Care Unit), which has resistance to a wide range of antibiotics, especially Carbapenems. Among the most important resistance mechanisms of this bacteria against carbapenems are MexAB-OprM efflux pump. Therefore, the aim of this study was to evaluate the g...
Introduction: One of the important factors causing nosocomial infections is drug-resistant Staphylococcus aureus strain, so correspondingly, having norA efflux pump is one of the bacterial's ability to generate drug resistance. Iron has been used as a nanoparticle with antimicrobial activity against bacteria. The aim of this study was to investigate the effect of iron oxide nanoparticles synthe...
The efflux pump system has been suggested as an important mechanism in the drug resistance of Mycobacterium tuberculosis (MTB). In this study, molecular analysis of five genes in the efflux pump system of MTB isolates from Korean patients was performed in order to identify appropriate molecular targets. In this study, 35 culture-positive specimens were included. PCR was performed for five efflu...
background: shigella spp. are gram negative bacteria, which are of global public health importance. the growing of multidrug-resistant shigella isolates are a major problemaround the world. methods: overall, 50 isolates of shigella spp. from children diarrheic stools were studied. the isolates were identified and confirmed using biochemical, serological and molecular methods (ipah, wbgz and rfc...
Background and purpose: The increasing emergence of multidrug resistance among Klebsiella pneumoniae nosocomial isolates has limited the therapeutic options in treatment of infections caused by these bacteria. The beta-lactamases, efflux pumps and porins constitute the major defense mechanisms of antibiotic resistance of these bacteria. The aims of the present study were detection of OqxA an...
The accessory genomes of many pathogenic bacteria include ABC transporters that scavenge metal by siderophore uptake and contribute to antimicrobial resistance multidrug efflux. There are mechanistic recently recognized structural similarities between importer proteins efflux pumps. Here we investigated the influence YbtPQ on Klebsiella pneumoniae . is encoded in yersiniabactin cluster a preval...
Quinolone antibiotics have been commonly used to treat cases of multiple antibiotic resistance. Unfortunately, quinolone so much resisted by infectious bacterial agents. This study aimed evaluate the susceptibility some clinical isolates E. coli and determination plasmid-encoded resistance genes.
 Our results showed plasmid quinolone-resistance genes in following prevalence: qnr genes: S (...
The molecular resistance mechanism of Aspergillus oryzae (A. oryzae) under arsenate (As(V)) stress was investigated by comparative transcriptome analysis. In total, 4911 differentially expressed genes (DEGs) A. were detected As(V) stress, including 2103 up-regulated and 2808 down-regulated genes. Genes induced involved in metal ion binding transportation, redox homeostasis, efflux carrier, DNA ...
Background: The in vivo radiation-induced bystander effects (RIBE) at the developmental, genetic, and epigenetic levels have been well demonstrated using model plant Arabidopsis thaliana (A. thaliana). However, the mechanisms underlying RIBE in plants are not clear, especially lacking a comprehensive knowledge about the genes and biological pathways involved in the RIBE in plants. Materials and...
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