This paper describes an Envisioning System (EvS) designed to help rural communities contemplate landscape level changes. Simulations and models project current conditions into the future according to the constraints of scenario-based planning and available land use choices. Possible futures are represented through visual (2D, 3D and iconic) indicators. This paper defines four distinct world vie...

BACKGROUND In recent years, there is considerable evidence of a relationship between the sensorimotor disorder restless legs syndrome (RLS) and pain disorders, including migraine and fibromyalgia. An association between multi-site pain and RLS has been reported in adult women. In the current study, we explored the association between musculoskeletal (MSK) pain and RLS in a large cohort of young...

Aims of this study were to determine the normal range of absolute and relative Hertel exophthalmometric values (EVs) in a Chinese Han population. This population-based cross-sectional study consisted of 2010 healthy Han Chinese (1051 females and 959 males) aged between 8-87 years living in Shenyang, Northeast China, including 515 children (aged 8-14 years), 517 teenagers (aged 15-19 years), 582...

The battery of electric vehicles (EV) can be charged from the power grid or discharged back to it. Parking lots can aggregate hundreds of EVs which makes them a significant and flexible load/generation component in the grid. In a smart grid environment, the smart parking lot (SPL) can benefit from the situation of the simultaneous connection to the EVs and power grid. This paper proposes a new ...

INTRODUCTION Restless legs syndrome (RLS) affects 5-15% of adults, but is often unrecognized and consequently misdiagnosed. The International Restless Legs Scale (IRLS) has been developed and validated to assess the severity of RLS. Currently, the most common treatment for RLS is levodopa, but this may lead to augmentation of symptoms. Pramipexole has been developed as an alternative treatment ...

background and objective : restless legs syndrome (rls) is a sleep disorder with an association to sleep quality. we investigated the sleep quality in patients with rls among health-care workers with or without shift work. materials and methods : all female health-care workers (n = 540) in four educational hospitals were enrolled in this cross-sectional study. international rls study group (irl...

Accumulating evidence shows that extracellular vesicles (EVs) produced by mesenchymal stem/stromal cells (MSCs) exert their therapeutic effects in several disease models. We previously demonstrated that MSCs suppress autoimmunity in models of type 1 diabetes (T1D) and experimental autoimmune uveoretinitis (EAU). Therefore, here, we investigated the therapeutic potential of MSC-derived EVs using...

Glioblastoma cells secrete extra-cellular vesicles (EVs) containing microRNAs (miRNAs). Analysis of these EV miRNAs in the bio-fluids of afflicted patients represents a potential platform for biomarker development. However, the analytic algorithm for quantitative assessment of EV miRNA remains under-developed. Here, we demonstrate that the reference transcripts commonly used for quantitative PC...

The heart is known for its resistance to cancer. Although different conjectures have been proposed to explain this phenomenon, none has been tested. We propose that the heart microenvironment may exert anti-cancer properties. So, our objective was to test the anti-oncogenic potential of cardiac-derived extracellular vesicles (EVs). For that EVs secreted by cardiosphere-derived cells (CDCs, hear...