Our research studies data suggest that, there were significant variations in the observed biochemical parameters. The level of TBARS in ethanol intoxicated rats increased two fold when compared with the control animals. The levels of GSH, SOD and CAT decreased significantly in the ethanol intoxicated rats. The level of GPx was increased in the ethanol intoxicated rats. The value of vitamin E in...

The alcoholic extract of fresh leaves of the plant Eclipta alba (Ea), previously reported for is hepatoprotective activity was fractionated into three parts to chemically identify the most potent bioactive fraction. The hepatoprotective potential of the fraction prepared from extract was studied in vivo in rats and mice against carbon tetrachloride induced hepatotoxicity. The hepatoprotective a...

The anti-inflammatory effect of the plant of Eclipta alba (Family - Asteraceae) was evaluated using carrageenin, mediators such as histamine and serotonin induced paw oedema, and cotton pellet induced granuloma tests for their effect on acute and chronic phase inflammation models in rats. Maximum inhibition (55.85%) was noted at the dose of 500 mg/kg after 3 hr of drug treatment in carrageenin ...

Eclipta prostrata (EP) is often prescribed in combination with glucocorticoid to treat glomerular nephritis, nephrotic syndrome, and IgA nephropathy in clinical practice of Traditional Chinese Medicine. Previous studies from our laboratory revealed that coadministration of EP significantly increased the plasma concentration of prednisolone while decreased the level of cotreated prednisone in ra...

Anxiety is a most common emotional disorder affecting 20% of adult population worldwide. Eclipta alba is having memory enhancing quality & traditionally used for this purpose. Since paucity of data available for this clinical use, the present work was undertaken to study the anti anxiety & sedative effects of Ethanolic extract of leaves of Eclipta alba(EEEA) in albino rats using thiopental sodi...

Tewtrakul, S., Subhadhirasakul, S., Kummee, S Anti-HIV-1 integrase activity of medicinal plants used as self medication by AIDS patients Songklanakarin J. Sci. Technol., 2006, 28(4) : 785-790 The extracts of selected medicinal plants used as self medication by AIDS patients were investigated for their inhibitory activities against HIV-1 integrase (HIV-1 IN) using the multiplate integration assa...

Eclipta alba is a medicinal herb, also known as Bhringraj belonging to family Asteraceae. The plant has hepatoprotective, antimicrobial and hair growth promoting properties. The effect of various phytohormones on in-vitro callus induction and shoot regeneration in Eclipta alba from leaf explant was evaluated. The sterilized explants were inoculated on MS medium supplemented with different conce...

One flavonoid, diosmetin (1), and two isoflavonoids, 3′-hydroxybiochanin A (2) and 3′-O-methylorobol (3), were isolated from the methanol extract of Eclipta prostrata L. by a bioactivity-guided fractionation technique using primary cultures of mouse osteoblasts as an in vitro assay system. All three compounds significantly increased osteoblast differentiation as assessed by the alkaline phospha...