Introduction: Despite similar histopathological features, peripheral giant cell granuloma (PGCG) and central giant cell granuloma (CGCG) differ in their biological behavior. PGCG and CGCG are hemorrhagic/vascular lesions, clinically and microscopically. Angiogenesis is necessary for the growth and development of lesions and affects their clinical behavior. CD105 is a useful vascular marker for...

Objective(s): To investigate the effect of miR-103 on the angiogenesis of ischemic stroke rats via targeting vascular endothelial growth factor (VEGF) at the molecular level. Materials and Methods: Rat models had received the middle cerebral artery occlusion (MCAO) or sham operation before grouping, and cell models of oxygen-glucose deprivation (OGD) were performed. FITC-dextran, matrigel, and ...

Vascular endothelial growth factor (VEGF) is a multifunctional cytokine with distinct functions in angiogenesis, lymphangiogenesis, vascular permeability, and hematopoiesis. VEGF is a highly conserved, disulfide-bonded dimeric glycoprotein of 34 to 45 kDa produced by several cell types including fibroblasts, neutrophils, endothelial cells, and peripheral blood mononuclear cells, particularly T ...

vascular endothelial growth factor (vegf) is a multifunctional cytokine with distinct functions in angiogenesis, lymphangiogenesis, vascular permeability, and hematopoiesis. vegf is a highly conserved, disulfide-bonded dimeric glycoprotein of 34 to 45 kda produced by several cell types including fibroblasts, neutrophils, endothelial cells, and peripheral blood mononuclear cells, particularly t ...

purpose : to determine the association between retinal vascular diameter and its branching angles with diabetic retinopathy (dr) stages in diabetic patients methods : a descriptive analytic cross-sectional study was conducted in 62 diabetic patients (120 eyes) referred to farabi eye hospital between june 2008 and december 2009. digital fundus photography pictures were imported into photoshop so...

The role of oxidized high-density lipoprotein (oxHDL) and the protective effects of adiponectin in terms of vascular calcification is not well established. This study was conducted to investigate the effects of oxHDL with regards to inflammation and vascular calcification and to determine the protective role of adiponectin in attenuating the detrimental effects of oxHDL. Cell viability, mineral...

background and objective: vascular endothelial growth factor (vegf) and its receptors (vegf-r1 and r2) are major regulators of angiogenesis. this study was designed to assess serum levels of vegf and vegf-r1 and their prognostic significance in newly diagnosed childhood acute leukemia. materials and methods: for this purpose, vegf and vegf-r1 were determined using enzyme linked immuno-sorbant a...

Objective(s): The purpose of this study was to detect the protective effects of adiponectin on coagulation dysfunction and its mechanism in sepsis of rats.Materials and Methods: The experimental samples were composed of sham group,   model group that was underwent cecal ligation and puncture (CLP) and three adiponectin treatment groups that treated by adiponectin with different dose (72 μg/kg, ...