Endothelin-converting enzyme-1 (ECE-1) cleaves big endothelins, as well as bradykinin and beta-amyloid peptide. Several isoforms of ECE-1 (a-d) have been identified to date; they differ only in their NH(2) terminus but share the catalytic domain located in the COOH-terminal end. Using quantitative PCR, we found ECE-1d to be the most abundant type in several endothelial cells (EC) types. In addi...

BACKGROUND There is growing evidence that early childhood education (ECE) interventions can reduce the loss of developmental potential of disadvantaged children in low- and middle-income countries (LAMIC). Less attention has been paid to the potential of these programmes to prevent child mental health problems and promote child well-being. METHODS Peer-reviewed journal articles describing con...

Algorithm for SNR Estimation In Rician Fading Channels D. Sreenivasa Rao, Department of ECE, St.Ann’s college of Engg & Tech., JNTUK, Chirala. Email: [email protected] Ch. Jessy Beulah, Department of ECE, St.Ann’s college of Engg & Tech., JNTUK, Chirala. Email: [email protected] G. Kumar Chaitanya, Department of ECE, St.Ann’s college of Engg & Tech., JNTUK, Chirala. Email: chaitanya940@g...

Endothelin-1 (ET-1) could play a role in the regulation of aldosterone secretion of the human adrenal gland. The presence of the endothelin-converting enzyme 1 (ECE-1) and ET-1 suggests that there is a local ET system in the adrenal cortex, but the in situ synthesis of ET-1 remains to be confirmed. The cellular distribution of the whole ET system was evaluated in 20 cases of aldosterone-produci...

BACKGROUND The purpose of the present study was to retrospectively evaluate the effects of extracapsular extension (ECE) on the benefits of post-mastectomy radiation therapy (PMRT) for groups of patients with varying numbers of positive axillary nodes (1-3, 4-9 and ≥10 positive axillary nodes). METHODS A total of 1220 axillary node-positive patients who had received mastectomy were involved i...

Endothelin-converting enzyme-1c (ECE-1c) is a membrane metalloprotease involved in endothelin-1 synthesis, which has been shown in vitro to have a role in breast, ovary and prostate cancer cell invasion. N-terminal end of ECE-1c displays three putative phosphorylation sites for the protein kinase CK2. We studied whether CK2 phosphorylates N-terminal end of ECE-1c as well as whether this has a r...

The purpose of this study was to examine the frequency and relationship between responsive feeding practices used during early childhood education (ECE) mealtimes high-quality teaching teacher characteristics. We found variation in teachers’ use practices. Teachers were more often observed using role modeling than supporting eating self-regulation. Programs that implemented family style meal se...

The vasoconstrictive peptide endothelin-1 (ET-1) is expressed in human epidermis at the gene and protein levels and plays an important role in stimulating pigmentation via its increased secretion by keratinocytes following ultraviolet B (UVB) irradiation. However, one or more biological mechanisms underlying the secretion of ET-1 by keratinocytes in human skin have never been evaluated. In mamm...

BACKGROUND Extracapsular extension (ECE) of disease from cervical lymph nodes (LNs) is an important prognostic factor for head and neck cancers; moreover, the presence of ECE has been shown to be a criterion for the addition of chemotherapy to postoperative radiation. METHODS We reviewed the frequency of ECE in the Surveillance, Epidemiology, and End Results (SEER) registry database, particul...

Endothelin-converting enzyme (ECE) is the key enzyme in the production of the potent vasoconstrictor endothelin from its inactive precursor big endothelin. To date, no other physiological peptide substrate has been identified for ECE. Here, by using Chinese hamster ovary (CHO) cells transfected with rat ECE-1 cDNA, we have established that ECE can hydrolyse the vasodilator bradykinin. The hydro...