Despite recent advances in antibiotic therapy, sepsis remains a major clinical challenge in intensive care units. Here we examined the anti-inflammatory and antioxidant effects of Ecballium elaterium (EE) on brain, and explored its therapeutic potential in an animal model of sepsis-associated encephalopathy (SAE) [induced by cecal ligation and puncture (CLP)]. Thirty rats were divided into thre...

The problem of the uncontrolled spread alien plant species matured in world second half 20th century, and recent decades it has become main threat to biological diversity various regions world. Prevention Invasions is a new urgent task field nature protection, which determines relevance study. purpose study determine predict distribution area invasive plants, based on use following methods: com...

The best medium for callus proliferation from hypocotyl and cotyledon explants of aseptically grown seedlings of two Egyptian landraces of rare wild plants, Ecballium elaterium and Cucumis prophetarum was found to be Murashige and Skoog (MS) medium supplemented with 0.1-0.5 mg/l NAA in combination with BA at 2 mg/l. On the other hand, MS medium supplemented with 2 mg/l BA, 60 mg/l adenine sulfa...

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Background: Ecballium elaterium is endemic to the northwestern Iran and its fruit is traditionally used for therapeutic purposes in Iran. The toxicological and phytochemical characteristics of the Iran’s Ecballium elaterium have not been investigated so far. Objective: Study on some toxicological and phytochemical features of the Iran’s Ecballium elaterium fruit 90% ethanol extract. Method: ...

Objectives Cucurbitacins exhibit a range of anti-cancer functions. We investigated the effects of cucurbitacins D, E, and I purified from Ecballium elaterium (L.) A. Rich fruits on some apoptotic and autophagy genes in human gastric cancer cell line AGS. Materials and Methods Using quantitative reverse transcription PCR (qRT-PCR), the expression of LC3, VEGF, BAX, caspase-3, and c-MYC genes w...