Numerous herbs have been used successfully in treating dermatologic disorders for thousands years and still widely used because it is easy to find, cheap and to avoid the side effects and complications of topical steroids. Terminalia chebula, commonly found in India and Southeast Asia, is thought to be effective for treating several diseases including inflammation and reported as an anti-oxidan...

introduction: chronic otitis media (com), a persistent and durable inflammation and infection of the middle ear, is a common disorder. alterations in the contralateral ear in sufferers have been observed in recent years. because only a few studies have been reported in this area, we performed this study in order to assess alterations in the contralateral ear of patients with com.   materials an...

microRNAs (miRNAs) are regulators of differentiation and development of inner ear cells. Mutations in miRNAs lead to deafness in humans and mice. Among inner ear pathologies, inflammation may lead to structural and neuronal defects and eventually to hearing loss and vestibular dysfunction. While the genetic factors of these pathways have not been defined, autoimmunity participates in these proc...

OME, middle ear disease with many denominations, is a subacute or chronic inflammation by multifactorial etiology, characterized by the presence of serous, mucous, or mixed, non-infected secretion, persistent for more than three months in the middle ear. The incidence is higher in children (ratio children / adults = 10/1), particularly pre-school (61%) than school age (22%), occurs mainly in wi...

One feature of allergic asthma, the EAR (early allergic reaction), is not present in the commonly used mouse models. We therefore investigated the mediators involved in EAR in a guinea-pig in vivo model of allergic airway inflammation. Animals were sensitized using a single OVA (ovalbumin)/alum injection and challenged with aerosolized OVA on day 14. On day 15, airway resistance was assessed af...

Background and Objective: Regarding side effects of acute and especially chronic inflammation and incomplete treatment of patients suffering from these side effects, the new and effective strategies are needed. For this purpose, in the present study, we scientifically evaluate an introduced folk herb Urtica dioica, for treatment of inflammation. Materials and Methods: The Sham, control and trea...

Otitis media with effusion (OME), also called glue ear, is characterised by a collection of fluid in the middle-ear cleft. there is chronic inflammation but without signs of acute inflammation. OME is the most common cause of hearing impairment (and the most common reason for elective surgery) in childhood, where it usually follows an episode of acute otitis media (AOM). It is uncommon in adult...

Otitis media with effusion (OME), also called glue ear, is characterised by a collection of fluid in the middle-ear cleft. there is chronic inflammation but without signs of acute inflammation. OME is the most common cause of hearing impairment (and the most common reason for elective surgery) in childhood, where it usually follows an episode of acute otitis media (AOM). It is uncommon in adult...