نتایج جستجو برای: e3

تعداد نتایج: 11331  

Journal: :Temas agrarios 2022

El mango cv. Tommy Atkins es cultivado en el departamento del Tolima, principalmente, lugar donde expresa su mejor comportamiento agronómico y calidad de la fruta. objetivo fue evaluar estado nutricional las plantas cuantificar extracción nutrientes por fruta función orden suelo se cultiva. Las concentraciones cada nutriente variaron entre fases muestreadas órgano (hojas, flor fruto) (Entisol e...

Journal: :Structure 2006
Chad A Brautigam R Max Wynn Jacinta L Chuang Mischa Machius Diana R Tomchick David T Chuang

The 9.5 MDa human pyruvate dehydrogenase complex (PDC) utilizes the specific dihydrolipoamide dehydrogenase (E3) binding protein (E3BP) to tether the essential E3 component to the 60-meric core of the complex. Here, we report crystal structures of the binding domain (E3BD) of human E3BP alone and in complex with human E3 at 1.6 angstroms and 2.2 angstroms, respectively. The latter structure sho...

2002
Kaori Suzuki Ramón Alemany Masato Yamamoto David T. Curiel

Purpose: The initial development of conditionally replicative adenoviruses (CRAds) for cancer treatment has aimed at achieving selective replication in and killing of malignant cells. Other aspects such as the potentiation of the cytolytic capacity have also been investigated but still require new endeavors. As an extension of our prior work, we analyzed the effect of the E3 region, which inclu...

Journal: :Nihon Naibunpi Gakkai zasshi 1984
K Tsukamoto

Although several studies have been reported on the synthesis of steroids in the fetus, the metabolism and conjugation of estrogens in the fetus is not completely known. In this study serum levels of estetrol (E4), estetrol glucosiduronate (E4-G), estriol (E3) and estriol-16-glucosiduronate (E3-16-G) were measured by R.I.A. in maternal peripheral vein blood (MPV), umbilical artery blood (UA) and...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه لرستان - دانشکده کشاورزی 1390

به منظور بررسی تاثیر اتفون و کود نیتروژن روی صفات کمی و کیفی سورگوم شیرین رقم سوفرا، آزمایشی به صورت کرت های یک بار خرد شده در قالب طرح بلوک های کامل تصادفی با سه تکرار در ایستگاه تحقیقات کشاورزی دانشگاه اصفهان اجرا شد. آزمایش با 4 سطح کود نیتروژنه (0، 100، 200 و 300 کیلوگرم اوره در هکتار) به عنوان عامل اصلی و 4 غلظت اتفون (0، 800، 1000 و 1200 پی پی ام) به عنوان عامل فرعی انجام گرفت. نتایج نشان...

2014
Niraj Kumar Jha Saurabh Kumar Jha Rohan Kar Rashmi K Ambasta Pravir Kumar

NDD: Neurodegenerative Disorders; ER: Endoplasmic Reticulum; UPS: Ubiquitin Proteasome System; ROS: Reactive Oxygen Species; AD: Alzheimer’s Disease; PD: Parkinson’s Disease; MS: Multiple Sclerosis; HD: Huntington’s Disease; ALS: Amyotrophic Lateral Sclerosis; PS: Presenilin; APP: Amyloid beta (A4) Precursor Protein; MARK1: Microtubule Affinity-Regulating Kinase 1; SOD-1: Superoxide Dismutase 1...

2016
Ruisheng Jiang Xiangmin Zeng Shihang Sun Zhijun Ma Ximing Wang

BACKGROUND The aim of this study was to investigate whether the anisotropy parameters are helpful in the detection and discrimination of breast cancers, and to determine its value in predicting the risk of cancers. MATERIAL AND METHODS There were 56 patients with 56 lesions (34 malignant, 22 benign) included in the study. DTI was performed in every patient and apparent diffusion coefficient (AD...

Journal: :Journal of virology 2011
José González-Santamaría Michela Campagna María Angel García Laura Marcos-Villar Dolores González Pedro Gallego Fernando Lopitz-Otsoa Susana Guerra Manuel S Rodríguez Mariano Esteban Carmen Rivas

The vaccinia virus (VACV) E3 protein is essential for virulence and has antiapoptotic activity and the ability to impair the host innate immune response. Here we demonstrate that E3 interacts with SUMO1 through a small ubiquitin-like modifier (SUMO)-interacting motif (SIM). SIM integrity is required for maintaining the stability of the viral protein and for the covalent conjugation of E3 to SUM...

Journal: :Molecular cell 2012
Andreas Werner Annette Flotho Frauke Melchior

RanBP2/Nup358 is an essential protein with roles in nuclear transport and mitosis, and is one of the few known SUMO E3 ligases. However, why RanBP2 functions in vivo has been unclear: throughout the cell cycle it stably interacts with RanGAP1*SUMO1 and Ubc9, whose binding sites overlap with the E3 ligase region. Here we show that cellular RanBP2 is quantitatively associated with RanGAP1, indica...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2013
Mark Windheim Jennifer H Southcombe Elisabeth Kremmer Lucy Chaplin Doris Urlaub Christine S Falk Maren Claus Janine Mihm Myles Braithwaite Kevin Dennehy Harald Renz Martina Sester Carsten Watzl Hans-Gerhard Burgert

The E3 transcription unit of human adenoviruses (Ads) encodes immunomodulatory proteins. Interestingly, the size and composition of the E3 region differs considerably among Ad species, suggesting that distinct sets of immunomodulatory E3 proteins may influence their interaction with the human host and the disease pattern. However, to date, only common immune evasion functions of species C E3 pr...

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